生物来源
Salmonella enterica (Serotype typhimurium)
质量水平
形式
lyophilized powder
纯化方式
gel-filtration chromatography
杂质
<1% Protein
颜色
white to faint yellow
溶解性
water: 0.90-1.10 mg/mL, hazy to turbid, colorless to faintly yellow
运输
ambient
储存温度
2-8°C
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一般描述
本品从鼠伤寒沙门氏菌中提取，经凝胶过滤纯化。来源菌株为 ATCC 7823。
应用
脂多糖（LPS）是革兰氏阴性细菌细胞壁的特征组分。LPS及其脂质A部分通过Toll样受体4（TLR4）刺激先天免疫系统的细胞，Toll样受体 4是Toll样受体蛋白家族的成员，其识别常见的病原体相关分子模式（PAMP）。
生化/生理作用
脂多糖 (LPS) 定位于膜的外层，在无荚膜的菌株中暴露于细胞表面。它们有助于外膜的完整性，并保护细胞免受胆盐和亲脂性抗生素的操作。
制备说明
本品可溶于水 (5 mg/mL) 或细胞培养基 (1 mg/mL)，得到淡黄色浑浊溶液。涡旋并加热至 70-80 oC 后，在盐水中获得了更浓缩但仍浑浊的溶液 (20 mg/mL)。脂多糖是在每种溶剂中形成胶束的分子。在水和磷酸盐缓冲盐水中观察到浑浊溶液。有机溶剂不能提供更清晰的溶液。甲醇产生浑浊的带有悬浮物的混悬液，而水产生均匀的浑浊溶液。
相关产品
产品编号
说明
价格
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Barbara Chirullo et al.
Frontiers in microbiology, 6, 985-985 (2015-10-07)
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商品
Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.
相关内容
Lipopolysaccharide (LPS) is a major component of Gram-negative bacteria, important for microbiological research.
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