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安全信息

L2023

Sigma-Aldrich

亮肽素 三氟乙酸盐

powder, ≥90% (HPLC)

别名:

Acetyl-Leu-Leu-Arg-al 三氟乙酸盐

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About This Item

经验公式（希尔记法）:
C20H38N6O4 · xC2HF3O2
CAS号:
147385-61-3
分子量:
426.55 (free base basis)
MDL编号:
MFCD00133458
UNSPSC代码:
12352202
PubChem化学物质编号:
329817397
NACRES:
NA.77
价格与库存信息目前不能提供

产品名称

亮肽素 三氟乙酸盐, ≥90% (HPLC), microbial

生物来源

microbial

质量水平

200

方案

≥90% (HPLC)

表单

powder

溶解性

H2O: 10 mM (Solutions are stable only a few hours. Stock solutions are stable up to 6 months at −20 °C.)

储存温度

−20°C

SMILES字符串

OC(=O)C(F)(F)F.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C=O

InChI

1S/C20H38N6O4.C2HF3O2/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;3-2(4,5)1(6)7/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);(H,6,7)/t15-,16-,17-;/m0./s1

InChI key

WUHGBZVQELGOMH-FRKSIBALSA-N

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1 of 4

此商品
CRM46304CRM18917CRM18920
F.A.M.E. Mix C8 - C24, certified reference material, ampule of 100 mg (Neat)

CRM18918

F.A.M.E. Mix

Aflatoxin Mix certified reference material, in methanol (varied conc.), ampule of 5 × 1 mL

CRM46304

Aflatoxin Mix

F.A.M.E. Mix C14 - C22, certified reference material,  wt. % (varied conc.), ampule of 100 mg

CRM18917

F.A.M.E. Mix

F.A.M.E. Mix C8 - C22, certified reference material, ampule of 100 mg (Neat)

CRM18920

F.A.M.E. Mix

format

mixture

format

multi-component solution

format

multi-component solution

format

multi-component solution

Quality Level

100

Quality Level

300

Quality Level

100

Quality Level

100

grade

certified reference material, TraceCERT®

grade

certified reference material, TraceCERT®

grade

certified reference material, TraceCERT®

grade

certified reference material, TraceCERT®

storage temp.

-10 to -25°C

storage temp.

2-8°C

storage temp.

-10 to -25°C

storage temp.

-10 to -25°C

packaging

ampule of 100 mg (Neat)

packaging

ampule of 5 × 1 mL

packaging

ampule of 100 mg

packaging

ampule of 100 mg (Neat)

生化/生理作用

丝氨酸和半胱氨酸蛋白酶抑制剂。抑制纤溶酶、胰蛋白酶、木瓜蛋白酶、钙蛋白酶和组织蛋白酶B。不抑制胃蛋白酶、组织蛋白酶A和D、凝血酶或α-糜蛋白酶。有效浓度为10-100 μM。
丝氨酸和半胱氨酸蛋白酶抑制剂。抑制纤溶酶、胰蛋白酶、木瓜蛋白酶、钙蛋白酶和组织蛋白酶B。不抑制胃蛋白酶、组织蛋白酶A和D、凝血酶或α-糜蛋白酶。有效浓度为10-100 μM。已有许多研究使用亮抑酶肽来预防因听觉过度刺激或耳毒性抗生素庆大霉素引起的听力损失。[1](耳蜗毛细胞的丧失被认为是由钙蛋白酶介导的。)

分析说明

由于在溶液中形成互变异构异构体，亮抑酶肽在 HPLC 上产生多个峰。大多数污染肽是外消旋亮抑酶肽。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品
  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000401297
    0000401297
    0000395822
    0000374433
    0000325073

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    Javier Manzano-Lopez et al.
    PloS one, 17(2), e0263617-e0263617 (2022-02-11)
    Intracellular trafficking through the secretory organelles depends on transient interactions between cargo proteins and transport machinery. Cytosolic coat protein complexes capture specific luminal cargo proteins for incorporation into transport vesicles by interacting with them indirectly through a transmembrane adaptor or
    Maryam Amirazodi et al.
    Iranian journal of basic medical sciences, 25(2), 254-262 (2022-06-04)
    High-intensity interval training (HIIT) is a shape of interval training that provides ameliorated athletic capacity and has a good effect on health. Resveratrol is a natural polyphenol abundant in grapes and red wine and has been demonstrated to apply various
    John Cherrington Carmen et al.
    Frontiers in microbiology, 2, 1-1 (2011-07-01)
    The regulation of mitochondrial permeability, a key event in the initiation of apoptosis is governed by the opposing actions of the pro- and anti-apoptotic members of the BCL2-family of proteins. The BCL2-family can be classified further based on the number
    Cellular expression and antimicrobial function of a phylogenetically conserved novel histone 1x-like protein on mouse cells: a potential new class of pattern recognition receptor.
    Evans, D.L., et al.
    Journal of Neurochemistry, 86, 133-141 (2009)
    N Korn et al.
    Poultry science, 81(7), 1077-1085 (2002-08-07)
    A monoclonal antibody (4C7/2E4) that binds to an antigen located on the midpiece of turkey spermatozoa has been produced and characterized. The antibody was also reactive to antigens on the midpiece of chicken, Japanese quail, and bobwhite quail spermatozoa but
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