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Merck
CN

L1164

Sigma-Aldrich

亚油醇乙醇胺

≥98%, ethanol solution

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About This Item

CAS号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥98%

形式

ethanol solution

分子量

apparent mol wt 323.5

运输

wet ice

储存温度

−20°C

SMILES字符串

CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCO

InChI

1S/C20H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h6-7,9-10,22H,2-5,8,11-19H2,1H3,(H,21,23)/b7-6-,10-9-

InChI key

KQXDGUVSAAQARU-HZJYTTRNSA-N

生化/生理作用

亚麻酰乙醇酰胺(LE)是一种脂肪酸乙醇酰胺,存在于清酒糟中。它通过阻止核因子 κB (NF-κB) 信号传导而具有抗炎作用。LE 被认为是治疗接触性皮炎的有益药物。

制备说明

为了更改溶剂,在温和的氮气流下蒸发乙醇,并立即加入选择的溶剂。

象形图

FlameExclamation mark

警示用语:

Danger

危险声明

危险分类

Eye Irrit. 2 - Flam. Liq. 2

WGK

WGK 3

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品

分析证书(COA)

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Joe Palandra et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(22), 2052-2060 (2009-06-19)
A sensitive and selective liquid chromatography tandem mass spectrometry (LC\MS\MS) method has been developed for the simultaneous quantification in human plasma of the endocannabinoid anandamide (AEA) and three other related ethanolamides, linoleoyl ethanolamide (LEA), oleoyl ethanolamide (OEA), and palmitoyl ethanolamide
Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor.
L Hanus et al.
Journal of medicinal chemistry, 36(20), 3032-3034 (1993-10-01)
The endogenous cannabimimetic eicosanoid, anandamide, induces arachidonate release in J774 mouse macrophages.
V Di Marzo et al.
Advances in experimental medicine and biology, 407, 341-346 (1997-01-01)
Thi Ai Diep et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 25(2), 765-774 (2010-10-21)
This study was undertaken to investigate the link between dietary fat content and intestinal levels of anorectic N-acylethanolamines (NAEs), including oleoylethanolamide (OEA), palmitoylethanolamide (PEA), and linoleoylethanolamide (LEA). Male rats were fed high-fat diets (HFDs) with variable percentages of fat [20-45%
Harald S Hansen et al.
Biochemical pharmacology, 78(6), 553-560 (2009-05-06)
Anandamide and the other N-acylethanolamines, e.g. oleoylethanolamide (OEA), palmitoylethanolamide (PEA), and linoleoylethanolamide (LEA), may be formed by several enzymatic pathways from their precursors, which are the N-acylated ethanolamine phospholipids. The exact enzymatic pathways involved in their biosynthesis in specific tissues

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