K4769
Kojibiose
≥98% (HPLC)
别名:
α-D-Glc-(1→2)-D-Glc, 2-O-α-D-Glucopyranosyl-D-glucose
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关于此项目
经验公式（希尔记法）:
C12H22O11
化学文摘社编号:
分子量:
342.30
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
InChI
1S/C12H22O11/c13-1-4(16)7(17)8(18)5(2-14)22-12-11(21)10(20)9(19)6(3-15)23-12/h2,4-13,15-21H,1,3H2
SMILES string
OCC(O)C(O)C(O)C(OC1OC(CO)C(O)C(O)C1O)C=O
InChI key
PZDOWFGHCNHPQD-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
technique(s)
HPLC: suitable
color
white to off-white
solubility
water: 5 mg/mL, clear, colorless
storage temp.
−20°C
Quality Level
Application
Kojibiose, a disaccharide product of glucose caramelization and an inhibitor of plant glucosidase I, may be used to help identify and characterize glucosidase I enzymes involved in terminal deglycosylation of high-mannose oligosaccharides. Kojibiose may be used as a substrate to study the biological species, enzymes and catabolic processes that catabolize it as an energy source. Kojibiose may be used to identify, differentiate and characterize kojibiose phosphorylase(s) (KP).
Biochem/physiol Actions
Kojibiose is an inhibitor of plant glucosidase I. It inhibits the removal of terminal glucose from (Glc)3(Man)9(GlcNAc)2.
Kojibiose is an inhibitor of plant glucosidase I. It inhibits the removal of terminal glucose from the high-mannose oligosaccharide (Glc)3(Man)9(GlcNAc)2, either from the free oligosaccharide or from the oligosaccharide attached to a protein via N-linkage.
Other Notes
To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Satoshi Okada et al.
The FEBS journal, 281(3), 778-786 (2013-11-22)
Glycoside hydrolase (GH) family 65 contains phosphorylases acting on maltose (Glc-α1,4-Glc), kojibiose (Glc-α1,2-Glc), trehalose (Glc-α1,α1,-Glc), and nigerose (Glc-α1,3-Glc). These phosphorylases can efficiently catalyze the reverse reactions with high specificities, and thus can be applied to the practical synthesis of α-glucosyl
Wouter F J Hogendorf et al.
Bioorganic & medicinal chemistry, 18(11), 3668-3678 (2010-04-23)
In this paper the synthesis of an Enterococcus Faecalis teichoic acid (TA) hexamer is presented. The key kojibiosyl-glycerol phosphoramidite building block was obtained by condensation of thioglucose donors, provided with various protecting groups at the C2 hydroxyl function with an
Jong-Hyun Jung et al.
Journal of bacteriology, 196(5), 1122-1131 (2014-01-07)
A unique gene cluster responsible for kojibiose utilization was identified in the genome of Pyrococcus sp. strain ST04. The proteins it encodes hydrolyze kojibiose, a disaccharide product of glucose caramelization, and form glucose-6-phosphate (G6P) in two steps. Heterologous expression of
Jarred Yasuhara-Bell et al.
Microorganisms, 8(3) (2020-03-11)
Rathayibacter toxicus is a Gram-positive, nematode-vectored bacterium that infects several grass species in the family Poaceae. Unique in its genus, R. toxicus has the smallest genome, possesses a complete CRISPR-Cas system, a vancomycin-resistance cassette, produces tunicamycin, a corynetoxin responsible for
S Ogawa et al.
Carbohydrate research, 307(1-2), 83-95 (1998-07-11)
Two kojibiose-type pseudo-disaccharides and a trisaccharide, containing a 5-amino-1,2,3,4-cyclopentanetetrol derivative or valienamine, linked by way of nitrogen bridges to the sugar residues, have been designed and synthesized as processing alpha-glucosidase I inhibitors. Synthesis of the pseudo-disaccharides was carried out starting
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