推荐产品
生物来源
human plasma
质量水平
检测方案
≥95% (SDS-PAGE)
形式
lyophilized powder
分子量
64000 Da
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
human ... KNG1 (includes EG:3827)
应用
Kininogen, low molecular weight from human plasma has been used to study rMASP-1 (recombinant mannose-binding lectin-associated serine protease 1)-mediated cleavage of LK (low molecular weight kininogen). It has been used as a standard for protein identification in milk-proteomics study.
生化/生理作用
LMW kininogen is a major extracellular cysteine proteinase inhibitor. Tissue kallikrein releases bradykinin, a potent bronchoconstrictor and vasoactive agent, from both HMW and LMY kininogen.
外形
Lyophilized from a solution in sodium acetate and sodium chloride.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
Delphine Vincent et al.
Frontiers in genetics, 6, 360-360 (2016-01-23)
Milk is a complex fluid whose proteome displays a diverse set of proteins of high abundance such as caseins and medium to low abundance whey proteins such as ß-lactoglobulin, lactoferrin, immunoglobulins, glycoproteins, peptide hormones, and enzymes. A sample preparation method
József Dobó et al.
PloS one, 6(5), e20036-e20036 (2011-06-01)
Bradykinin (BK), generated from high-molecular-weight kininogen (HK) is the major mediator of swelling attacks in hereditary angioedema (HAE), a disease associated with C1-inhibitor deficiency. Plasma kallikrein, activated by factor XIIa, is responsible for most of HK cleavage. However other proteases
Xavier Charest-Morin et al.
Pharmacology research & perspectives, 3(2), e00119-e00119 (2015-06-04)
Tissue kallikrein (KLK-1), a serine protease, initiates the release of bradykinin (BK)-related peptides from low-molecular weight kininogen. KLK-1 and the BK B2 receptor (B2R) mediate beneficial effects on the progression of type 2 diabetes and renal disease, but the precise
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门