K3250
犬尿胺 二氢溴酸
monoamine oxidase substrate, fluorogenic, ≥97% (TLC), crystalline
别名:
3-（2-氨基苯基）-3-氧代丙胺
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关于此项目
经验公式（希尔记法）:
C9H12N2O · 2HBr
化学文摘社编号:
分子量:
326.03
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
MDL number:
产品名称
犬尿胺 二氢溴酸, crystalline
SMILES string
Br.NCCC(=O)c1ccccc1N
InChI
1S/C9H12N2O.BrH/c10-6-5-9(12)7-3-1-2-4-8(7)11;/h1-4H,5-6,10-11H2;1H
InChI key
YUPVVZSYBUIDQR-UHFFFAOYSA-N
assay
≥97% (TLC)
form
crystalline
solubility
water: 50 mg/mL, clear to slightly hazy
storage temp.
−20°C
Quality Level
General description
单胺氧化酶底物
Application
二氢溴酸犬尿氨酸被用作单胺氧化酶的底物。
Biochem/physiol Actions
二氢溴酸犬尿氨酸是单胺氧化酶的底物。最终产物为荧光分光光度计在 380 nm 处测定的荧光可检测 4-羟基喹啉 (4-HOQ) 的形成。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Magdalena S Nel et al.
Bioorganic chemistry, 69, 20-28 (2016-09-24)
In the present study a series of fifteen 2-heteroarylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. These compounds are structurally related to series of heterocyclic chalcone derivatives which have previously been
Chronic dietary mercury exposure causes oxidative stress, brain lesions, and altered behaviour in Atlantic salmon (Salmo salar) parr
Berntssen MHG, et al.
Aquatic Toxicology (Amsterdam, Netherlands), 65(1), 55-72 (2003)
Synergistic antidepressant-like effect of ferulic acid in combination with piperine: involvement of monoaminergic system
Li G, et al.
Metabolic Brain Disease, 30(6), 1505-1514 (2015)
Evidence for the involvement of the noradrenergic system, dopaminergic and imidazoline receptors in the antidepressant-like effect of tramadol in mice
Jesse CR, et al.
Pharmacology, Biochemistry, and Behavior, 95(3), 344-350 (2010)
Paolo Guglielmi et al.
Molecules (Basel, Switzerland), 24(3) (2019-02-01)
New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B. The most important chiral compounds were separated into their single enantiomers and tested. The impact of
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