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Merck
CN

K3250

Sigma-Aldrich

犬尿胺 二氢溴酸

monoamine oxidase substrate, fluorogenic, ≥97% (TLC), crystalline

别名:

3-(2-氨基苯基)-3-氧代丙胺

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About This Item

经验公式(希尔记法):
C9H12N2O · 2HBr
CAS号:
分子量:
326.03
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.32

产品名称

犬尿胺 二氢溴酸, crystalline

方案

≥97% (TLC)

质量水平

表单

crystalline

溶解性

water: 50 mg/mL, clear to slightly hazy

储存温度

−20°C

SMILES字符串

Br.NCCC(=O)c1ccccc1N

InChI

1S/C9H12N2O.BrH/c10-6-5-9(12)7-3-1-2-4-8(7)11;/h1-4H,5-6,10-11H2;1H

InChI key

YUPVVZSYBUIDQR-UHFFFAOYSA-N

应用

二氢溴酸犬尿氨酸被用作单胺氧化酶的底物。

生化/生理作用

二氢溴酸犬尿氨酸是单胺氧化酶的底物。最终产物为荧光分光光度计在 380 nm 处测定的荧光可检测 4-羟基喹啉 (4-HOQ) 的形成。

底物

单胺氧化酶底物

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Zhanna V Chirkova et al.
Drug development research, 79(2), 81-93 (2018-03-24)
Hit, Lead & Candidate Discovery In recent studies, we have shown that pyrrolo[3,4-f]indole-5,7-dione and indole-5,6-dicarbonitrile derivatives act as good potency in vitro inhibitors of the monoamine oxidase (MAO) enzymes. To expand on these series and to further derive structure-activity relationships
Magdalena S Nel et al.
Bioorganic chemistry, 69, 20-28 (2016-09-24)
In the present study a series of fifteen 2-heteroarylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. These compounds are structurally related to series of heterocyclic chalcone derivatives which have previously been
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Jesse CR, et al.
Pharmacology, Biochemistry, and Behavior, 95(3), 344-350 (2010)

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