生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen ~35 kDa
种属反应性
rat, mouse, human
浓度
~1 mg/mL
技术
immunohistochemistry: suitable
western blot: 1:500-1:1,000
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
human ... KLK11(11012)
mouse ... Klk11(56538)
rat ... Klk11(292849)
一般描述
The gene KLK11 (kallikrein 11) encodes a member of the kallikrein gene family. The gene is mapped to human chromosome 19q13.4. It is found to be highly expressed in the prostate. It has been found to be present in biological fluids and in serum of patients with various cancers. KLK11 is also found to be expressed in stomach, trachea, skin, and colon.
免疫原
synthetic peptide corresponding to residues 68-82 of the human Kallikrein 11. This sequence is 86% identical in mouse and rat.
生化/生理作用
The gene KLK11 (kallikrein 11) encodes a putative serine protease that is overexpressed in prostate and ovarian cancer. It serves as a biomarker for prognosis of ovarian cancer. It can serve as a marker for distinguishing between prostate cancer and benign prostatic hyperplasia.
外形
solution in phosphate buffered saline, containing 0.02% sodium azide.
相关产品
产品编号
说明
价格
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
Human kallikrein 11: a new biomarker of prostate and ovarian carcinoma.
Diamandis EP
Cancer Research, 62, 295-300 (2002)
The usefulness of serum human kallikrein 11 for discriminating between prostate cancer and benign prostatic hyperplasia.
Nakamura T
Cancer Research, 63, 6543-6546 (2003)
Human kallikrein 11: an indicator of favorable prognosis in ovarian cancer patients.
Diamandis EP
Clinical Biochemistry, 37, 823-829 (2004)
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