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Merck
CN

K113

Ketamine hydrochloride/xylazine hydrochloride solution

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关于此项目

化学文摘社编号:
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:
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InChI

1S/C13H16ClNO.C12H16N2S.2ClH/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14;1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;;/h2-3,6-7,15H,4-5,8-9H2,1H3;3,5-6H,4,7-8H2,1-2H3,(H,13,14);2*1H

SMILES string

Cl.Cl.Cc1cccc(C)c1NC2=NCCCS2.CNC3(CCCCC3=O)c4ccccc4Cl

InChI key

IYJHJWJNWIPQFJ-UHFFFAOYSA-N

form

solution

drug control

USDEA Schedule III; stupéfiant (France); regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain)

color

colorless

storage temp.

2-8°C

Quality Level

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Biochem/physiol Actions

This is a solution of ketamine hydrochloride, an NMDA receptor antagonist, and xylazine hydrochloride, an α2- adrenergic receptor agonist.

Other Notes

Telephone orders are not accepted for this product.

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Liyuan Jiang et al.
Aging and disease, 11(3), 603-617 (2020-06-04)
The complex pathology of chronic thoracic spinal cord compression involves vascular and neuroarchitectural repair processes that are still largely unknown. In this study, we used synchrotron radiation microtomography (SRμCT) to quantitatively characterize the 3D temporal-spatial changes in the vascular and
Yuanlin He et al.
Cell death & disease, 8(5), e2817-e2817 (2017-05-26)
In mammalian ovaries, primordial follicles remain in a quiescent state until activation by the surrounding microenvironment. Ovarian intervention, for example, ovarian cystectomy, ovarian wedge resection or laser drilling therapies for polycystic ovarian syndrome, has long been reported to change follicular
J M Tepper et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 15(4), 3092-3103 (1995-04-01)
Evidence from electrophysiological studies has suggested an inhibitory interaction between GABAergic neurons in substantia nigra pars reticulata and dopaminergic neurons in pars compacta. However, that this inhibitory interaction is due to a projection from pars reticulata to pars compacta has
Ehsan Saboory et al.
Experimental physiology, 105(5), 783-792 (2020-02-14)
What is the central question of this study? Do changes in levels of angiogenesis-related mediators [vascular endothelial growth factor-A (VEGF-A), thrombospondin-1 (TSP-1) and nuclear factor-κB (NF-κB)] in the sciatic nerve mediate diabetic neuropathy in the streptozotocin-induced type 1 diabetic male rat?
I Soltesz et al.
Journal of neurophysiology, 70(1), 97-116 (1993-07-01)
1. Intracellularly recorded low- and high-frequency (4-6 and 25-50 Hz, respectively), rhythmic, spontaneous membrane potential oscillations were investigated in pyramidal neurons of the rat hippocampus in vivo, during theta (theta, 4-6 Hz) electroencephalographic (EEG) activity, under ketamine-xylazine anesthesia. 2. The

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