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方案
≥98% (HPLC)
颜色
white to off-white
溶解性
DMSO: ≥10 mg/mL
储存温度
2-8°C
InChI
1S/C24H26N2O6/c1-3-4-5-10-30-22-19(29-2)9-7-16-12-17(24(28)26-21(16)22)23(27)25-13-15-6-8-18-20(11-15)32-14-31-18/h6-9,11-12H,3-5,10,13-14H2,1-2H3,(H,25,27)(H,26,28)
InChI key
GRAJFFFXJYFVOC-UHFFFAOYSA-N
生化/生理作用
JTE-907 is a cannabinoid CB2 ligand (inverse agonist).
JTE-907 is a cannabinoid CB2 ligand (inverse agonist). CB2 cannabanoid receptors are expressed in periferal nerves and other non CNS tissues, but are not expressed in the brain. CB2 is believed to have a role in nociceptive pain, but additional functions pertaining to the immune system have yet to be determined. CB2 selective agonists and antagonists provide a necessary tool for functional analyses.
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