质量水平
检测方案
≥98% (HPLC)
形式
powder
储存条件
desiccated
颜色
tan
溶解性
DMSO: ≥20 mg/mL
储存温度
2-8°C
SMILES字符串
Cl.CCc1ccc(OCc2ccccc2C(=O)Nc3ccc4nc(C)cc(N)c4c3)cc1
InChI
1S/C26H25N3O2.ClH/c1-3-18-8-11-21(12-9-18)31-16-19-6-4-5-7-22(19)26(30)29-20-10-13-25-23(15-20)24(27)14-17(2)28-25;/h4-15H,3,16H2,1-2H3,(H2,27,28)(H,29,30);1H
InChI key
NQLIYKXNAXKMBL-UHFFFAOYSA-N
生化/生理作用
JTC-801 is a nociceptin/orphanin FQ peptide (NOP) receptor antagonist.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
G Delaney et al.
Journal of neuroendocrinology, 24(12), 1527-1541 (2012-07-28)
Central nociceptin/orphanin FQ (N/OFQ)-expressing neurones are abundantly expressed in the hypothalamus and limbic system and are implicated in the regulation of activity of the hypothalamic-pituitary-adrenal axis (HPA) and stress responses. We investigated the role of the endogenous N/OFQ receptor (NOP)
Keiichi Hiramoto et al.
Photodermatology, photoimmunology & photomedicine, 33(2), 84-91 (2017-01-01)
We previously reported that ultraviolet (UV) A eye irradiation reduces the ulcerative colitis induced by dextran sodium sulfate (DSS). This study examined the effects of UVA on colon carcinoma induced by azoxymethane (AOM) and DSS. We irradiated the eyes of
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