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Merck
CN

J2000

保幼激素III

≥65%, liquid, non-sterile

别名:

甲基法尼酯,10,11-环氧化物, C16-保幼激素, JH-III, 反,反-10,11-环氧-3,7,11-三甲基-2,6-十二碳二烯酸甲酯, 烟草天蛾激素

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关于此项目

经验公式(希尔记法):
C16H26O3
化学文摘社编号:
分子量:
266.38
UNSPSC Code:
51111800
NACRES:
NA.32
PubChem Substance ID:
EC Number:
246-072-9
Beilstein/REAXYS Number:
1316317
MDL number:
Biological source:
synthetic (organic)
Form:
liquid
Assay:
≥65% (HPLC)
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产品名称

保幼激素III, ≥65%, liquid, non-sterile

InChI key

QVJMXSGZTCGLHZ-ZPLWXOMKSA-N

InChI

1S/C16H26O3/c1-12(9-10-14-16(3,4)19-14)7-6-8-13(2)11-15(17)18-5/h7,11,14H,6,8-10H2,1-5H3/b12-7+,13-11+

SMILES string

COC(=O)\C=C(/C)CC\C=C(/C)CC[C@H]1OC1(C)C

biological source

synthetic (organic)

sterility

non-sterile

assay

≥65% (HPLC)

form

liquid

concentration

≥65%

technique(s)

activity assay: suitable

shipped in

ambient

storage temp.

−20°C

Quality Level

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Application

保幼激素 III 已用于:
  • 保幼激素对褶皱臂尾轮虫混交雌体的产生的影响
  • 研究保幼激素对成年蜜蜂头部 GB19811(假定的Takeout/保幼激素结合蛋白)mRNA 水平的影响
  • 研究保幼激素对地熊蜂促促性腺和生理功能的影响

Biochem/physiol Actions

JHBP(JH 结合蛋白)可保护JH(保幼激素)免受JH酯酶和环氧化物水解酶介导降解。它们还有助于将JH传递到靶组织。保幼激素(JHs) 是一组无环倍半萜类化合物,在某些昆虫谱系中,这些化合物的法尼醇骨架经过化学修饰,产生一系列同源激素。JH是昆虫发育和繁殖全方位必需的成分。它在社会性昆虫的变态和等级决定中具有关键作用。它可调节行为、多形性、幼虫和成虫滞育以及卵巢发育。保幼激素 III (JH III) 的倍半萜类骨架是通过蟑螂的经典甲羟戊酸(MVA)途径生物合成的。
控制昆虫的幼虫变态,包括保留幼体特征。

General description

研究领域:细胞信号传导

保幼激素III (JH III)是昆虫体内最普遍的保幼激素 (JH)。

hcodes

Hazard Classifications

Aquatic Chronic 4

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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José L Maestro et al.
Insect biochemistry and molecular biology, 40(9), 660-665 (2010-06-15)
Levels of juvenile hormone III (JH), FGLamide allatostatin peptides (ASTs), ASTs precursor (preproAST) mRNA and methyl farnesoate epoxidase (CYP15A1) mRNA were measured in embryos of the cockroach Blattella germanica. JH starts to rise just after dorsal closure, reaches maximal levels
Atul Pandey et al.
Neurobiology of sleep and circadian rhythms, 9, 100056-100056 (2020-12-29)
The circadian and endocrine systems influence many physiological processes in animals, but little is known on the ways they interact in insects. We tested the hypothesis that juvenile hormone (JH) influences circadian rhythms in the social bumble bee Bombus terrestris.
Keiji Matsumoto et al.
Royal Society open science, 8(2), 202242-202242 (2021-05-12)
Juvenile hormone (JH) plays important roles in almost every aspect of insect development and reproduction. JHs are a group of acyclic sesquiterpenoids, and their farnesol backbone has been chemically modified to generate a homologous series of hormones in some insect
J C Bede et al.
Plant physiology, 127(2), 584-593 (2001-10-13)
In most insect species, juvenile hormones regulate critical physiological processes such as metamorphosis and reproduction. In insects, these sesquiterpenoids are synthesized by retrocerebral endocrine organs, the corpora allata, via the classical mevalonate (MVA) pathway. One of these compounds, juvenile hormone
Gallardo et al.
Journal of experimental marine biology and ecology, 252(1), 97-107 (2000-08-30)
Juvenile hormone (JH) and serotonin (5-HT) were previously shown to enhance mictic (sexual) female production of the rotifer Brachionus plicatilis in batch cultures. To explore the basis of these effects, experiments were conducted on isolated individuals. JH treatment of maternal

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