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Merck
CN
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文件

I9271

Sigma-Aldrich

5-（碘乙酰胺基）荧光素

≥90% purity (HPLC), powder

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别名:
5-IAF
经验公式（希尔记法）:
C22H14INO6
CAS号:
63368-54-7
分子量:
515.25
Beilstein:
6543244
UNSPSC代码:
12171500
PubChem化学物质编号:
329815467
NACRES:
NA.47

质量水平

200

检测方案

≥90% (HPLC)

形式

powder

溶解性

DMSO: 5 mg/mL

荧光

λex 492 nm; λem 515 nm (Mercaptoethanol adduct)
λex 493 nm; λem 522 nm (pH 9.2)

应用

diagnostic assay manufacturing
hematology
histology

储存温度

−20°C

SMILES字符串

Oc1ccc2c(Oc3cc(O)ccc3C24OC(=O)c5cc(NC(=O)CI)ccc45)c1

InChI

1S/C22H14INO6/c23-10-20(27)24-11-1-4-15-14(7-11)21(28)30-22(15)16-5-2-12(25)8-18(16)29-19-9-13(26)3-6-17(19)22/h1-9,25-26H,10H2,(H,24,27)

InChI key

UATCLPJEZJKNHE-UHFFFAOYSA-N

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相关类别

一般描述

5-(碘乙酰氨基)荧光素是一种硫醇反应性荧光素衍生物。

应用

5-(碘乙酰氨基)荧光素用于合成荧光标记的细胞器（细胞核和核基质）、蛋白质和肽，包括酶。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Actin is the principal component of microfilaments. Its assembly/disassembly is essential for cell motility, cytokinesis, and a range of other functions. Recent evidence suggests that actin is present in the nucleus where it may be involved in the regulation of
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Mitogen-activated protein kinase (MAPK) activation depends on a linear binding motif found in all MAPK kinases (MKK). In addition, the PB1 (Phox and Bem1) domain of MKK5 is required for extracellular signal regulated kinase 5 (ERK5) activation. We present the
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