所有图片(3)
About This Item
经验公式（希尔记法）:
C22H14INO6
CAS号:
分子量:
515.25
Beilstein:
6543244
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47
推荐产品
产品名称
5-（碘乙酰胺基）荧光素, ≥90% (HPLC)
质量水平
方案
≥90% (HPLC)
表单
powder
技术
titration: suitable
颜色
yellow to orange
溶解性
DMSO: 5 mg/mL
荧光
λex 492 nm; λem 515 nm (Mercaptoethanol adduct)
λex 493 nm; λem 522 nm (pH 9.2)
应用
diagnostic assay manufacturing
hematology
histology
储存温度
−20°C
SMILES字符串
Oc1ccc2c(Oc3cc(O)ccc3C24OC(=O)c5cc(NC(=O)CI)ccc45)c1
InChI
1S/C22H14INO6/c23-10-20(27)24-11-1-4-15-14(7-11)21(28)30-22(15)16-5-2-12(25)8-18(16)29-19-9-13(26)3-6-17(19)22/h1-9,25-26H,10H2,(H,24,27)
InChI key
UATCLPJEZJKNHE-UHFFFAOYSA-N
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一般描述
5-(碘乙酰氨基)荧光素是一种硫醇反应性荧光素衍生物。
应用
5-(碘乙酰氨基)荧光素用于合成荧光标记的细胞器（细胞核和核基质）、蛋白质和肽，包括酶。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Identification of the 5-iodoacetamidofluorescein reporter site on the Na,K-ATPase.
Tyson PA
The Journal of Biological Chemistry, 264, 726-726 (1989)
Multisite phosphorylation of the Saccharomyces cerevisiae filamentous growth regulator Tec1 is required for its recognition by the E3 ubiquitin ligase adaptor Cdc4 and its subsequent destruction in vivo.
Bao MZ
Eukaryotic Cell, 9, 31-31 (2010)
Lisa M Landino et al.
The Journal of biological chemistry, 279(33), 35101-35105 (2004-06-09)
Alterations in the redox status of proteins have been implicated in the pathology of several neurodegenerative conditions including Alzheimer and Parkinson diseases. We report that peroxynitrite- and hydrogen peroxide-induced disulfides in the neuron-specific microtubule-associated proteins tau and microtubule-associated protein-2 are
Lisa M Landino et al.
Free radical biology & medicine, 36(4), 497-506 (2004-02-21)
Cumulative oxidative damage to proteins coupled with a decrease in repair has been implicated in the pathology of several neurodegenerative diseases. Herein we report that peroxynitrite-induced disulfides in porcine brain tubulin are repaired by the thioredoxin reductase system composed of
Chris Chumsae et al.
Analytical chemistry, 81(15), 6449-6457 (2009-07-04)
Each human IgG1 antibody contains a total of thirty-two cysteine residues. In theory, all of them are involved in disulfide bonds, and no free sulfhydryl should be detected. However, literature has suggested that the presence of low levels of free
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