产品名称
Interferon αA from mouse, ≥95%, recombinant, expressed in E. coli, buffered aqueous solution, suitable for cell culture
biological source
mouse
recombinant
expressed in E. coli
assay
≥95%
form
buffered aqueous solution
mol wt
20 kDa
technique(s)
cell culture | mammalian: suitable
color
colorless
shipped in
dry ice
storage temp.
−70°C
Quality Level
Gene Information
mouse ... Ifna3(110218)
Analysis Note
The biological activity is determined in the cytopathic effect inhibition assay using mouse L929 cells with encephalomyocarditis virus. The cytopathic effect of 50% is produced with approximately 1 unit/ml interferon. The units are determined with respect to NIH international standard reference for mouse interferon α.
Biochem/physiol Actions
Cytokine with anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities.
Cytokine with anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities. Type I Interferons are a closely related family of 165-172 amino acid proteins that are produced by leukocytes (α subtypes), fibroblasts (β subtypes), lymphocytes (ω subtypes) and ruminant embryos (τ subtypes). Interferon induces a variety of effects on target cells including antiviral, antiproliferative and immunomodulatory activities.
Packaging
Minimum 1x105 units/vial.
Physical form
Solution in phosphate buffered saline containing 0.1% bovine serum albumin.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
低风险生物材料
常规特殊物品
此项目有
Interferon standards and general abbreviations.
S Pestka
Methods in enzymology, 119, 14-23 (1986-01-01)
S Rubinstein et al.
Journal of virology, 37(2), 755-758 (1981-02-01)
A convenient assay for interferons based on reduction of cytopathic effect was developed. The number of manipulations and the lengths of the various incubation steps were reduced to a minimum. The assay is simple to perform and can be completed
A convenient and rapid cytopathic effect inhibition assay for interferon.
P C Familletti et al.
Methods in enzymology, 78(Pt A), 387-394 (1981-01-01)
相关内容
Datasheet
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