一般描述
IgG 抗体亚型是免疫系统中含量最丰富的血清免疫球蛋白。由 B 细胞分泌，存在于血液和细胞外液中，可防止细菌、真菌和病毒引起的感染。母体 IgG 通过胎盘转移至胎儿，
胎盘对新生儿抵抗感染的免疫防御至关重要。
胎盘对新生儿抵抗感染的免疫防御至关重要。
人 IgG 抗体主要促进体液免疫应答，如补体结合、胎盘转运和吞噬作用等。来自人血清的 IgG 可作为试剂级免疫球蛋白的经济替代品，在这种情况下，不一定要求达到高纯度。也可用于免疫电泳。本品在人体内具有反应性。
应用
纯化的人 IgG 可作为参比抗原、标准品、封闭剂或包被蛋白，用于包括 免疫分析、斑点免疫结合、免疫印迹、免疫扩散和免疫电泳在内的多种免疫测定。其他应用包括用于制备免疫原和固相免疫吸附剂的起始物料。在不需要高纯度的应用中，技术级人 IgG 可作为试剂级免疫球蛋白的经济替代品。在各种研究中使用来自人血清的 IgG 作为免疫分析标准品。在流式细胞仪中使用 200 μg/ml 至 1 mg/mL 的人 IgG 浓度范围进行封闭。
外形
0.01 M 磷酸盐缓冲液 (pH 7.2) 中的溶液，含 15 mM 叠氮化钠
免责声明
除非我们的目录或产品随附的其他公司文档中另有说明，我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人或动物的任何类型的消费或应用。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
Simone F A Wouters et al.
Bioconjugate chemistry, 31(3), 656-662 (2020-01-08)
Bioluminescent antibodies represent attractive detection agents in both bioanalytical assays and imaging. Currently, their preparation relies on genetic fusion of luciferases to antibodies or nonspecific chemical conjugation strategies. Here, we report a generic method to generate well-defined covalent antibody-luciferase conjugates
Gerlândia Neres Pontes et al.
FEMS immunology and medical microbiology, 47(3), 405-413 (2006-07-29)
We evaluated the ability of human maternal and cord serum antibodies to protect mice challenged with live Escherichia coli serotype O6:K2ac (E. coli O6). Mice received paired maternal or cord serum pools before a challenge with E. coli O6 to
Ruben Godoy-Silva et al.
Biotechnology and bioengineering, 102(4), 1119-1130 (2008-10-30)
The effect of hydrodynamic forces on animal cell cultures, while extensively studied, still lacks significant, fundamental understanding. A previous manuscript reported on the acute exposure of CHO cells to hydrodynamic forces in a second generation convergent-divergent microfluidic device (Mollet et
K M Dziegielewska et al.
The Histochemical journal, 33(8), 443-451 (2002-04-05)
Fetuin, a foetal protein of unknown function, has been shown to be expressed in both the immune and nervous systems, especially during development. Here, we show for the first time, that fetuin is abundantly present in many cells of the
A T Nagao et al.
Scandinavian journal of immunology, 53(6), 602-609 (2001-06-26)
A high prevalence of systemic infections caused by enterobacteria such as Escherichia coli is observed during the neonatal period. Lipopolysaccharide (LPS) is one of the major factors responsible for septic shock caused by these Gram-negative bacteria. We have recently demonstrated
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