I8000
2-碘苯甲酸
≥98% (TLC)
别名:
IBA
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关于此项目
线性分子式:
OIC6H4CO2H
化学文摘社编号:
分子量:
264.02
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
206-159-4
MDL number:
Beilstein/REAXYS Number:
1939973
产品名称
2-碘苯甲酸,
InChI key
IFPHDUVGLXEIOQ-UHFFFAOYSA-N
InChI
1S/C7H5IO3/c9-7(10)5-3-1-2-4-6(5)8-11/h1-4H,(H,9,10)
SMILES string
OC(=O)c1ccccc1[I]=O
assay
≥98% (TLC)
form
powder
color
white to off-white
mp
230 °C (dec.) (lit.)
storage temp.
−20°C
Quality Level
Application
色氨酸肽键断裂。
Biochem/physiol Actions
碘苯甲酸 (IBA) 可用于研究酶的结构和活性。IBA 用作氧化剂，氧化邻近巯基为酶内的二硫化物（半胱氨酸残基），导致其失活或构象变化。IBA 也用于裂解色氨酸肽键。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
M Fontecave et al.
Biochemical and biophysical research communications, 168(2), 659-664 (1990-04-30)
The active form of protein B2, the small subunit of ribonucleotide reductase from E. Coli, contains a binuclear non heme iron center and a tyrosyl radical. MetB2 is an inactive form that lacks the radical but retains the Fe(III) center.
Neal N Reed et al.
Bioorganic & medicinal chemistry letters, 12(15), 2047-2049 (2002-07-13)
A series of soluble and insoluble polymer supported versions of the versatile oxidizing reagent IBX has been prepared. Each of the reagents were evaluated for their efficiency in the conversion of benzyl alcohol to benzaldehyde. Results from this study were
J O Moskaug et al.
The Journal of biological chemistry, 266(4), 2652-2659 (1991-02-05)
When the enzymatically active A-fragment of diphtheria toxin is translocated to the cytosol, the B-fragment inserts into the membrane in such a way that a 25-kDa polypeptide becomes shielded from proteases added to the external medium. We have attempted to
W F Liu et al.
Toxicology letters, 45(2-3), 289-298 (1989-02-01)
o-Iodosobenzoic acid (IBA), in a surfactant micellar medium, is a rapid and efficient catalyst for the hydrolysis of organophosphate (OP) esters. Since little is known about the toxicity of IBA, a primary screen of neurobehavioral toxicity was evaluated in male
C Longo et al.
The International journal of biochemistry, 24(1), 133-143 (1992-01-01)
1. o-Iodosobenzoic acid (IOB) caused the formation of a disulfide bridge between SH1 and SH2 groups of myosin SF1 rendering inactive its ATPase activity. 2. IOB at high concentrations provoked fragmentation of SF1 at its tryptophan residues. 3. The main
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