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Merck
CN

I7508

肌醇 -肌醇

≥99% (GC), BioReagent

别名:

meso-肌醇, 环己六醇, 肌糖

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关于此项目

经验公式（希尔记法）:
C6H12O6
化学文摘社编号:
87-89-8
分子量:
180.16
UNSPSC Code:
12352201
NACRES:
NA.21
PubChem Substance ID:
24896116
EC Number:
201-781-2
Beilstein/REAXYS Number:
1907329
MDL number:
MFCD00077932

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产品名称

肌醇 -肌醇, ≥99% (GC), BioReagent

InChI key

CDAISMWEOUEBRE-GPIVLXJGSA-N

InChI

1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H/t1-,2-,3-,4+,5-,6-

SMILES string

O[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

vapor density

6.2 (vs air)

product line

BioReagent

assay

≥99% (GC)

form

powder

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

color

white

mp

222-227 °C (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

application(s)

agriculture
life science and biopharma
metabolomics
sample preparation
sample preparation
vitamins, nutraceuticals, and natural products

Quality Level

300

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相关类别

Application

肌醇已用于：
  • 在液体基础培养基中作为培养物肌醇饥饿的对照品
  • 作为胚胎培养用合成输卵管液培养基的补充
  • 作为富士维生素溶液的组分，制备用于甘蔗苗生长的营养培养基

Biochem/physiol Actions

肌醇（MI）作为一种渗透剂，可协助细胞膜和髓鞘片结构的形成。它是膜磷酸肌醇和磷脂的重要前体。在阿尔茨海默症、脑胶质瘤病和糖尿病等几种脑部疾病中，观察到肌醇（MI）浓度升高。肌醇是膜磷脂的组成部分，糖基磷脂酰肌醇锚可以将糖蛋白结合到细胞膜和磷酸肌醇第二信使。
膜磷脂、糖基化磷脂酰肌醇锚定蛋白、磷酸肌醇酯第二信使的成分,其中锚定蛋白可将糖蛋白锚定到细胞膜上。

Features and Benefits

  • 适于细胞生物学、代谢组学和生物化学研究
  • 用途广泛，适用于各种实验室和研究应用

General description

Myo-肌醇，也称为i-肌醇，是一种糖醇，在动物和微生物中均起到生长因子的作用。作为一种假维生素，它不像其他维生素是′人体必需的，虽然对于机体有重要作用，但缺乏后不会′导致生病。这种多醇含量丰富，是真核细胞二级信使的结构组分，在胰岛素信号传导和细胞骨架传导中起重要作用。

Myo-肌醇是结构脂质的关键组分，包括磷脂酰肌醇(PI)及其各种磷酸盐，如磷脂酰肌醇磷酸(PIP)。可用作渗透剂、细胞培养基补充剂、营养物质、磷酸肌醇磷脂酶C抑制剂和代谢物。它参与信号传导，可刺激肿瘤细胞分化，在细胞膜磷脂、细胞质脂蛋白和细胞核中也有分布，具有潜在的化学预防作用。Myo-肌醇是功能丰富的化合物，适合用于细胞培养、代谢组学和生物化学研究，助力探索细胞过程及其对健康和疾病的影响。
肌醇（MI）是一种糖样分子，主要存在于人脑胶质细胞中。 

Other Notes

为了全面了解我们针对客户研究提供的各种单糖产品，建议您访问我们的碳水化合物分类页面。
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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
WXBF7993V
WXBF7764V
WXBF6979V
WXBF6448V
WXBF5716V

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Robert B Campenot et al.
Nature protocols, 4(12), 1869-1887 (2009-12-17)
The compartmented culture, in which primary neurons plated in a proximal compartment send their axons under silicone grease barriers and into left and right distal compartments, has enhanced the experimental capabilities of neuronal cultures. Treatments can be applied separately to
M Hallman et al.
Early human development, 10(3-4), 245-254 (1985-01-01)
According to animal studies myoinositol decreases surfactant phosphatidylglycerol and increases phosphatidylinositol. In the present study lung effluent phospholipids and serum myoinositol were analyzed in respiratory distress syndrome (RDS, 19 cases), in other lung disease (6 cases) and in 22 newborn
M Utriainen et al.
Journal of neuro-oncology, 62(3), 329-338 (2003-06-05)
The signal of choline containing compounds (Cho) in proton magnetic resonance spectroscopy (1H-MRS) is elevated in brain tumors. [11C]choline uptake as assessed using positron emission tomography (PET) has also been suggested to be higher in brain tumors than in the
C Servo et al.
Diabetologia, 11(6), 575-580 (1975-12-01)
Cerebrospinal fluid (CSF) or CSF and plasma levels of sorbitol, 1,5-anhydroglucitol and myoinositol of diabetic and non-diabetic patients with normal kidney function and of diabetic and non-diabetic patients with impaired kidney function were measured by gas-liquid chromatography. The CSF sorbitol
Pascal M Groenen et al.
American journal of obstetrics and gynecology, 189(6), 1713-1719 (2004-01-08)
The purpose of this study was to investigate the maternal and children's myo-inositol, glucose, and zinc status in association with spina bifida risk. Sixty-three mothers and 70 children with spina bifida and 102 control mothers and 85 control children were
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Product Information Sheet - I7508

Product Information Sheet

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