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方案
≥98% (HPLC)
表单
powder
mp
114 °C
溶解性
ethanol: 20 mg/mL
1 M HCl: 5 mg/mL
储存温度
2-8°C
SMILES字符串
CC1CNCCN1S(=O)(=O)c2cccc3cnccc23
InChI
1S/C14H17N3O2S/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14/h2-6,10-11,16H,7-9H2,1H3
InChI key
BDVFVCGFMNCYPV-UHFFFAOYSA-N
基因信息
human ... CALCRL(10203)
rat ... Calcrl(25029)
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生化/生理作用
Inhibitor of cyclic nucleotide dependent protein kinase (PKA) and protein kinase C.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
The Journal of experimental medicine, 209(11), 2017-2031 (2012-10-10)
Acute megakaryoblastic leukemia (AMKL) is a heterogeneous disease generally associated with poor prognosis. Gene expression profiles indicate the existence of distinct molecular subgroups, and several genetic alterations have been characterized in the past years, including the t(1;22)(p13;q13) and the trisomy
PloS one, 8(2), e54841-e54841 (2013-02-19)
We observed the therapeutic effect of Fasudil and explored its mechanisms in experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). Fasudil, a selective Rho kinase (ROCK) inhibitor, was injected intraperitoneally at 40 mg/kg/d in early and late
Journal of fungi (Basel, Switzerland), 5(3) (2019-07-20)
Despite improvement in the prognosis of HIV/AIDS (human immunodeficiency virus/acquired immune deficiency syndrome) patients on antiretroviral therapy (ART), cryptococcal meningitis (CM) still causes 10-15% mortality among HIV-infected patients. The immunological impact of ART on the CD4+ and CD8+ T cell
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The CARMA1/CARD11-BCL10-MALT1 (CBM) complex bridges T and B cell antigen receptor (TCR/BCR) ligation to MALT1 protease activation and canonical nuclear factor κB (NF-κB) signaling. Using unbiased mass spectrometry, we discover multiple serine phosphorylation sites in the MALT1 C terminus after
Brain : a journal of neurology, 135(Pt 11), 3355-3370 (2012-10-23)
Axonal degeneration is one of the earliest features of Parkinson's disease pathology, which is followed by neuronal death in the substantia nigra and other parts of the brain. Inhibition of axonal degeneration combined with cellular neuroprotection therefore seem key to
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