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Merck
CN

I6635

Sigma-Aldrich

单克隆抗分泌成分(IgA) 小鼠抗

clone GA-1, ascites fluid

别名:

IgA Antibody, Secretory Component Antibody

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.46

生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

ascites fluid

抗体产品类型

primary antibodies

克隆

GA-1, monoclonal

包含

15 mM sodium azide

种属反应性

human

技术

indirect ELISA: 1:10,000

同位素/亚型

IgG1

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

一般描述

分泌成分是单链糖蛋白,可以自由存在或作为分泌免疫球蛋白A(SIgA)的成分存在。IgA调节共生肠道细菌与宿主免疫系统防御之间的生理平衡。它是产生最多的抗体同种型。IgAs主要分泌于肠粘膜,防止共生微生物侵入肠道
单克隆抗分泌成分(IgA)抗体对分泌型人IgA和游离分泌成分具有特异性。该抗体不与人IgG、IgM和IgE结合。

免疫原

从人初乳中纯化的分泌成分

应用

单克隆抗分泌成分(IgA)抗体已用于免疫组化分析和血清分析。
单克隆抗分泌成分(IgA)抗体适用于EIA和蛋白质印迹。该产品也可用于间接ELISA(1:10,000)。
成功使用该抗体的应用以及相关的同行评审论文如下所示。
染色质免疫沉淀分析(1篇论文)

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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储存分类代码

12 - Non Combustible Liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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分析证书(COA)

Lot/Batch Number

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访问文档库

Alpha Fardah Athiyyah et al.
Iranian journal of microbiology, 11(4), 300-304 (2019-11-14)
Probiotics and prebiotics are known to regulate immune responses. A synbiotic is a product that combines probiotics and prebiotics in a single dosage form. In this study, we attempt to present the effects of a multispecies synbiotic on intestinal mucosa
C G Engeland et al.
Brain, behavior, and immunity, 52, 11-17 (2015-09-01)
Stress-induced impairments of mucosal immunity may increase susceptibility to infectious diseases. The present study investigated the association of perceived stress, depressive symptoms, and loneliness with salivary levels of secretory immunoglobulin A (S-IgA), the subclasses S-IgA1, S-IgA2, and their transporter molecule
Influence of reactive oxygen species on secretory component in the intestinal epithelium during hyperoxia
Zhao M, et al.
Experimental and Therapeutic Medicine, 14(5), 4033-4040 (2017)
B Simell et al.
The Journal of infectious diseases, 183(6), 887-896 (2001-03-10)
Local antibodies probably contribute to defense against Streptococcus pneumoniae. This study examined whether pneumococcal carriage and acute otitis media (AOM) induce mucosal antibodies to potential vaccine candidates pneumococcal surface adhesin A (PsaA), pneumolysin (Ply), and pneumococcal surface protein A (PspA).
Min Zhao et al.
Experimental and therapeutic medicine, 14(5), 4033-4040 (2017-10-28)
Redox imbalance is established in various human diseases. Treatment of intestinal epithelial cells with hyperoxia for a prolonged period of time may cause serious effects on redox balance. Secretory component (SC) protein is secreted by intestinal epithelial cells, and has

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