质量水平
检测方案
≥98% (TLC)
形式
powder
杂质
≤5% Free sulfhydryl groups
mp
198-201 °C (lit.)
溶解性
H2O: 100 mg/mL
储存温度
2-8°C
SMILES字符串
N=C1SCCC1.Cl
InChI
1S/C4H7NS.ClH/c5-4-2-1-3-6-4;/h5H,1-3H2;1H
InChI key
ATGUDZODTABURZ-UHFFFAOYSA-N
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一般描述
2-氨基硫代乙烷盐酸盐(2-IT.HCl),一种蛋白质修饰试剂,通常用于将硫醇基团连接到蛋白质和肽上。用 2-IT 修饰的毛发角蛋白纤维的拉曼光谱分析。HCl 显示出新的二硫化物基团的形成。
应用
2-硫代乙烯基盐酸盐已用于合成硫醇化 PEG(聚(乙二醇))。它可用于合成 PLA-SH(聚乙二醇-硫醇)和 PLA-PEG-SH(聚乙二醇-聚乳酸-硫醇)。
伯胺的硫醇化试剂。在 pH 7-10 下,通过脒键反应,得到游离巯基。 可用于制备二硫化物和/或硫醚连接的缀合物。
其他说明
注意:脒键具有初始伯胺的正电荷。包含五个原子的连接臂。
警示用语:
Danger
危险声明
危险分类
Acute Tox. 3 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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