product name
艾地苯醌, ≥98% (HPLC)
质量水平
检测方案
≥98% (HPLC)
形式
powder
溶解性
methanol: 50 mg/mL, clear to slightly hazy
储存温度
room temp
SMILES字符串
O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O
InChI
1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3
InChI key
JGPMMRGNQUBGND-UHFFFAOYSA-N
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一般描述
艾地苯醌是一种短链苯醌类药物。
应用
艾地苯醌已用于:
- 处理用于药物治疗测定的突变肌纤蛋白 (mMYOC)细胞
- 验证 C2C12 二次细胞筛选测定
- 处理肥胖小鼠,测试艾地苯醌和 CoQ10 是否直接结合过氧化物酶体增殖物激活受体(PPAR)LBD、His 标记的 PPAR αδ 和γ LBD。
生化/生理作用
艾地苯醌用于治疗患有 Leber′遗传性视神经病变 (LHON)的青少年和成人的视力障碍。它可用作抗氧化剂。它有助于保护心肌免于氧化应激。
一种短链辅酶 Q 类似物,可通过介导电子从 N2 转移到氧来增强超氧化物的形成。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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