推荐产品
表单
solid
颜色
white
溶解性
DMSO: soluble 30 mg/mL
储存温度
−20°C
SMILES字符串
CCCC(=O)NCCc1c2-c3ccccc3Cn2c4ccc(OC)cc14
InChI
1S/C22H24N2O2/c1-3-6-21(25)23-12-11-18-19-13-16(26-2)9-10-20(19)24-14-15-7-4-5-8-17(15)22(18)24/h4-5,7-10,13H,3,6,11-12,14H2,1-2H3,(H,23,25)
InChI key
RQYIUGOJQFWLAZ-UHFFFAOYSA-N
基因信息
human ... MTNR1A(4543) , MTNR1B(4544)
生化/生理作用
Melatonin receptor agonist
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
Francisco Javier Navarro Gil et al.
The Journal of pharmacology and experimental therapeutics, 371(1), 186-190 (2019-08-03)
Melatonin has been shown to enhance tear secretion associated with dinucleotide diadenosine tetraphosphate. This study investigated the isolated action of melatonin and its analogs, agomelatine, N-butanoyl-2-(2-methoxy-6H-isoindolo[2,1-a]indol-11-yl) ethanamine (IIK7), and 5-methoxycarbonylamino-N-cetyltryptamine (5-MCA-NAT) (10 µl at 100 µM), on tear secretion when
Irene Reyes-Resina et al.
Cells, 9(1) (2020-01-16)
Experiments in the late nineties showed an inverse relationship in the eye levels of melatonin and dopamine, thereby constituting an example of eye parameters that are prone to circadian variations. The underlying mechanisms are not known but these relevant molecules
Hanan Awad Alkozi et al.
British journal of pharmacology, 177(9), 2090-2105 (2020-01-05)
Often, glaucoma presents with elevated eye hydrostatic pressure, which is regulated by endogenous melatonin. Phenylephrine increases cytoplasmic [Ca2+ ], via α1 -adrenoceptor activation, that is detrimental in glaucoma. The aims of this study were (a) to elucidate the role of
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