跳转至内容
Merck
CN

I5404

Sigma-Aldrich

IgG2,κ 来源于人类骨髓瘤血浆

purified immunoglobulin, >95% (SDS-PAGE)

别名:

人IgG2-κ

登录查看公司和协议定价


About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.46

生物来源

human

质量水平

偶联物

unconjugated

抗体形式

purified immunoglobulin

检测方案

>95% (SDS-PAGE)

运输

dry ice

储存温度

−20°C

正在寻找类似产品? 访问 产品对比指南

一般描述

IgG抗体亚型是免疫系统中含量最丰富的血清免疫球蛋白。它由B细胞分泌,存在于血液和细胞外液中,可防止细菌、真菌和病毒引起的感染。母体IgG通过胎盘转移到胎儿体内,胎盘对于新生儿的抗感染免疫防御至关重要。
人类骨髓瘤IgG2, κ是通过分级分离、离子交换以及亲和层析流程从人血浆中纯化出来的。

应用

纯化IgG2, κ;可用作免疫球蛋白校准品、参考抗原、封闭剂或包被蛋白,用于各种免疫分析,包括ELISA、点印迹免疫结合、蛋白质免疫印迹、免疫扩散、免疫电泳、血凝反应和细胞结合分析。人骨髓瘤IgG2,κa被用于表征人和小鼠抗体的三硫化物修饰 以及用于流式细胞术。

外形

溶于0.02 M Tris缓冲盐水,pH 8.0。

分析说明

可以通过免疫电泳和间接ELISA法进行鉴定。

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Jorn J Heeringa et al.
Allergy, 75(5), 1121-1132 (2019-10-07)
While treatment for atopic rhinitis is aimed mostly to relieve symptoms, only allergen-specific immunotherapy (AIT) is targeted to modify the natural history of allergic diseases. This results in sustained clinical tolerance, even when treatment has stopped. The immunomodulatory effects of
Jonatan Dewulf et al.
Cancers, 13(9) (2021-05-06)
The involvement of RANK/RANKL signaling in the tumor microenvironment (TME) in driving response or resistance to immunotherapy has only very recently been recognized. Current quantification methods of RANKL expression suffer from issues such as sensitivity, variability, and uncertainty on the
Sheng Gu et al.
Analytical biochemistry, 400(1), 89-98 (2010-01-21)
Trisulfides are a posttranslational modification formed by the insertion of a sulfur atom into a disulfide bond. Although reports for trisulfides in proteins are limited, we find that they are a common modification in natural and recombinant antibodies of all
Misty W Stevens et al.
mAbs, 6(2), 547-555 (2014-02-05)
Ch-mAb7F9, a human-mouse chimeric monoclonal antibody (mAb) designed to bind (+)-methamphetamine (METH) with high affinity and specificity, was produced as a treatment medication for METH abuse. In these studies, we present the preclinical characterization that provided predictive evidence that ch-mAb7F9
Zhongqi Zhang et al.
mAbs, 11(8), 1381-1390 (2019-08-15)
Human IgG antibodies containing terminal alpha 2,6-linked sialic acid on their Fc N-glycans have been shown to reduce antibody-dependent cell-mediated cytotoxicity and possess anti-inflammatory properties. Although terminal sialylation on complex N-glycans can happen via either an alpha 2,3-linkage or an

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门