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生物来源
human
质量水平
重组
expressed in E. coli
检测方案
≥95%
形式
buffered aqueous solution
分子量
19 kDa
包装
pkg of 20 μg
浓度
≥0.2 mg/mL
技术
cell culture | mammalian: suitable
杂质
endotoxin, tested
颜色
colorless
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... IFNA2(3440)
相关类别
应用
人干扰素-αA已被用于：
- 研究基孔肯亚病毒对干扰素介导的JAK（Janus激酶）-STAT（信号转导和转录活化因子）信号的影响
- 研究干扰素-α和PRK2（蛋白激酶C相关激酶2）抑制剂对丙型肝炎病毒复制的影响
- 比较红曲霉色素衍生物对丙型肝炎病毒复制的影响
生化/生理作用
具有抗病毒、抗增殖、免疫调节和促炎活性的细胞因子。I型干扰素是由白细胞（α亚型），成纤维细胞（β亚型），淋巴细胞（ω亚型）和反刍动物胚胎（τ亚型）产生的165-172个氨基酸蛋白的密切相关家族。干扰素可诱导靶细胞产生多种作用，包括抗病毒、抗增殖和免疫调节活性。
外形
以5 mM 乙酸钠，pH 4.0中的溶液形式提供。
分析说明
在细胞病变效应抑制试验中，使用含有水疱性口炎病毒（VSV）的MDBK细胞测定生物活性。用1单位/ml干扰素可产生50%的细胞病变效应。单位是根据WHO人干扰素αA国际标准参考确定的。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves
法规信息
常规特殊物品
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