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Merck
CN
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主要文件

安全信息

I3661

Sigma-Aldrich

Insulin-FITC labeled human

recombinant, expressed in yeast, lyophilized powder

别名:

FITC Insulin, Labeled Human Insulin

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About This Item

EC 号:
UNSPSC代码:
12352204
NACRES:
NA.83

重组

expressed in yeast

质量水平

表单

lyophilized powder
solid

组成

Insulin, ≥75% biuret

标记范围

≥1 mol FITC per mol insulin

运输

dry ice
dry ice

储存温度

−20°C
−20°C

一般描述

Insulin is a polypeptide hormone mainly secreted from pancreas when glucose level changes in the plasma. It is an anabolic hormone and enhances the generation of storage substances, for instance glycogen, fat and protein. It also induces glucose uptake by peripheral tissues, thereby controlling glucose levels in the plasma. Its main sites of action are liver, adipose tissue and muscle.

应用

Insulin-FITC labeled human has been used in primary endothelial cells from human adipose tissue microvasculature (HAMEC) to study insulin transcytosis.

外形

含有磷酸钠缓冲盐的冻干粉

储存分类代码

11 - Combustible Solids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

胰岛素激素类产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Cristina C Clement et al.
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Transport of tissue-derived lymphatic fluid and clearance by draining lymph nodes are pivotal for maintenance of fluid homeostasis in the body and for immune-surveillance of the self- and non-self-proteomes. Yet a quantitative analysis of nodal filtration of the tissue-derived proteome
Espinal J
Understanding Insulin Action: Principles and Molecular Mechanisms (1989)
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ACS nano, 16(6), 8729-8750 (2022-05-27)
Glioblastoma (GBM) is an aggressive primary brain cancer, with a 5 year survival of ∼5%. Challenges that hamper GBM therapeutic efficacy include (i) tumor heterogeneity, (ii) treatment resistance, (iii) immunosuppressive tumor microenvironment (TME), and (iv) the blood-brain barrier (BBB). The
Aaron L Glieberman et al.
Lab on a chip, 19(18), 2993-3010 (2019-08-30)
Pancreatic β cell function is compromised in diabetes and is typically assessed by measuring insulin secretion during glucose stimulation. Traditionally, measurement of glucose-stimulated insulin secretion involves manual liquid handling, heterogeneous stimulus delivery, and enzyme-linked immunosorbent assays that require large numbers
Hanwoong Woo et al.
Molecular brain, 11(1), 37-37 (2018-07-05)
Chronic stress is a psychologically significant factor that impairs learning and memory in the hippocampus. Insulin signaling is important for the development and cognitive function of the hippocampus. However, the relation between chronic stress and insulin signaling at the molecular

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