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Merck
CN

I3653

Sigma-Aldrich

Anti-Interferon β antibody produced in goat

affinity isolated antibody, lyophilized powder

别名:

Anti-IFN-β

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About This Item

MDL编号:
UNSPSC代码:
51111800
NACRES:
NA.41

生物来源

goat

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

lyophilized powder

种属反应性

human

技术

western blot: 0.1-2.0 μg/mL

UniProt登记号

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... IFNB1(3456)

一般描述

Type I interferons are proteins produced in response to inducers like viral infection and can be divided into α and β subtypes. IFN-β provokes high antiproliferation response in certain cells like embryonal carcinoma, melanoma and melanocytes. It also has high potency in treatment of multiple sclerosis and certain cancers. Anti-interferon β antibody can be used in western blot. Goat anti-interferon β antibody reacts specifically with human interferon-β and has shown no cross reactivity with recombinant human interferon-γ.

特异性

The antibody will neutralize the biological activity of recombinant human IFN-β. It will not block the biological activity of recombinant human IFN-α or IFN-γ.

免疫原

recombinant human IFN-β, expressed in Escherichia coli.

应用

Anti-interferon β antibody can be used in immunoblotting. It can also be used to neutralize the bioactivity of recombinant human interferon-β.

外形

Lyophilized from a solution in phosphate buffered saline containing carbohydrates.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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P Belhumeur et al.
Molecular and cellular biology, 13(5), 2846-2857 (1993-05-01)
In the current study, we have addressed the role of interferons (IFNs) in controlling the differentiation of pluripotent P19 embryonal carcinoma (EC) cells. Blocking IFN activity in the culture medium of differentiating cells with antibodies leads to a strong decrease

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