所有图片(4)
About This Item
经验公式（希尔记法）:
C19H21Cl2N3O · 2HCl
CAS号:
分子量:
451.22
Beilstein:
8176205
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.32
溶解性
DMSO: soluble
质量水平
适用性
suitable for Ames test in Salmonella and E. coli (Frameshift mutagenic standard)
储存温度
2-8°C
SMILES字符串
Cl[H].Cl[H].COc1ccc2nc3cc(Cl)ccc3c(NCCCNCCCl)c2c1
InChI
1S/C19H21Cl2N3O.2ClH/c1-25-14-4-6-17-16(12-14)19(23-9-2-8-22-10-7-20)15-5-3-13(21)11-18(15)24-17;;/h3-6,11-12,22H,2,7-10H2,1H3,(H,23,24);2*1H
InChI key
LMEMIKWTNPWYMI-UHFFFAOYSA-N
正在寻找类似产品? 访问 产品对比指南
相关类别
警示用语：
Danger
危险分类
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Carc. 1B
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
S De Flora et al.
Mutagenesis, 12(6), 431-435 (1997-12-31)
Multiple drug resistance (MDR) mechanisms are known to limit the effectiveness of some cancer chemotherapies, probably through enhancing P-glycoprotein-mediated drug efflux from mammalian cells. Similar mechanisms appear to act in other organisms, including bacteria, and may affect not only the
Richard Hampson et al.
Mutation research, 525(1-2), 1-9 (2003-03-26)
Mutagenesis screening, in which heritable traits are isolated following damage to the genome, is a powerful approach for investigating gene function. Among vertebrate model organisms, the zebrafish (Danio rerio) is ideally suited to mutagenesis screens. The success of large-scale screens
S A Amundson et al.
Mutation research, 284(2), 287-295 (1992-12-16)
Human lymphoblastoid cell lines derived from WI-L2 exhibit unexpected frequencies of diaminopurine (DAP) resistant mutants. The background mutant fractions of 10(-7) to 10(-8) in untreated cultures are much lower than the frequencies expected for loss of a heterozygous autosomal locus
W D Chen et al.
Journal of the National Cancer Institute, 92(6), 480-485 (2000-03-16)
Deficiency of DNA mismatch repair is a common feature of cancers exhibiting instability of microsatellite DNA sequences. Cancers with microsatellite instability are recognizable by their high rate of spontaneous frameshift mutations within microsatellite sequences, their resistance to killing by cytotoxic
M Watanabe et al.
Mutation research, 314(1), 27-37 (1994-01-01)
The specificity of frameshift mutations induced by several classes of chemical mutagens was determined using a collection of mutant E. coli lacZ genes. This collection can detect each of five kinds of specific frameshift events by scoring Lac+ revertant colonies.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门