推荐产品
生物来源
rat
质量水平
重组
expressed in E. coli
方案
≥97% (SDS-PAGE)
表单
lyophilized powder
分子量
15.5 kDa
包装
pkg of 0.1 mg
技术
cell culture | mammalian: suitable
杂质
endotoxin, tested
颜色
white
UniProt登记号
储存温度
−20°C
基因信息
rat ... Ifng(25712)
相关类别
应用
来自大鼠的干扰素-γ已被用于研究脂氧素A4和17(R)-消退素D1对培养的大鼠星形胶质细胞中脂多糖和干扰素-γ介导的肿瘤坏死因子释放的影响。在大鼠中，它已被用于处理INS-1细胞培养物以研究可将β-细胞复制或凋亡的频率转变为复制或凋亡比率的转化因子。
生化/生理作用
Ifng（干扰素-γ）在先天性和获得性免疫反应中可起重要作用，并有助于防御细菌、双态酵母和某些病毒的感染。它在大鼠栓塞性中风的缺血性损伤中被上调。在培养的大鼠肠粘膜微血管内皮细胞中，ifng负责诱导干扰素-α和干扰素-β的表达。
特点和优势
生物学活性是利用抗病毒检测体系对感染了EMC病毒的L-929细胞进行测量而得到的。
外形
从每1 μg细胞因子含有50 μg牛血清白蛋白的磷酸盐溶液经0.2 μm过滤后冻干的。
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
Meager, A. et al.
Lymphokines and Interferons, A Practical Approach, 129-129 (1987)
Sally Abdelmoaty et al.
PloS one, 8(9), e75543-e75543 (2013-10-03)
Lipoxins and resolvins have anti-inflammatory and pro-resolving actions and accumulating evidence indicates that these lipid mediators also attenuate pain-like behavior in a number of experimental models of inflammation and tissue injury-induced pain. The present study was undertaken to assess if
Zhen-Jie Wang et al.
iScience, 24(11), 103280-103280 (2021-11-13)
Nitric oxide (NO) is an important immune molecule that acts against extracellular and intracellular pathogens in most hosts. However, after the knockout of inducible nitric oxide synthase (iNOS -/-) in Sprague Dawley (SD) rats, these iNOS -/- rats were found
Hamid Reza Jafarinaveh et al.
Iranian journal of allergy, asthma, and immunology, 13(2), 125-130 (2013-12-18)
Increased levels of proinflammatory cytokines have been recorded after the onset of transient or permanent brain ischemia and are usually associated with exacerbation of ischemic injury. Embolic stroke model is more relevant to the pathophysiological situation in such patients, because
R Dijkema et al.
The EMBO journal, 4(3), 761-767 (1985-03-01)
The chromosomal immune interferon gene of the rat (IFN-gamma) was identified by screening a recombinant rat lambda phage library with a human IFN-gamma cDNA probe. In contrast to the genes of other rat IFNs, this rat IFN-gamma chromosomal gene contains
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门