推荐产品
一般描述
Immunoglobulin A (IgA) is the most abundant antibody isotype produced in humans. IgAs are heterogeneous and exist astwo IgA subtypes. It has the ability to form multimers by interacting with the joining (J) chain. It is present in large quantities in blood. Immunoglobulin A (IgA) antibodies protect mucosal surfaces against invading pathogens.
应用
IgA from human colostrum has been used to find out percent cross-selectivity values for lactoferrin immunosensors versus several common proteins contained in milk and saliva. It has also been used in western blotting.
IgA from human colostrum is a suitable ELISA standard used to estimate the concentrations of IgA in human B cell culture supernatants and in human blood, colostrum and cord blood samples.
生化/生理作用
IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears, colostrum and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces.
外形
Solution in 0.01 M Tris-HCl, 0.1 M sodium chloride, pH 8.0, containing 15 mM sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Tithipong Plangsangmas et al.
Animals : an open access journal from MDPI, 10(1) (2020-01-23)
Salivary immunoglobulin A (sIgA) has been proposed as a potential indicator of welfare for various species, including Asian elephants, and may be related to adrenal cortisol responses. This study aimed to distinguish circadian rhythm effects on sIgA in male and
Katie L Edwards et al.
Conservation physiology, 7(1), coy077-coy077 (2019-03-25)
Additional measures of well-being would be beneficial to the management of a variety of species in human care, including elephants. Immunoglobulin A (IgA) is an immune protein associated with pathogen defense, which has been demonstrated to decrease during times of
M Raux et al.
Journal of immunological methods, 222(1-2), 111-124 (1999-02-18)
Enzyme-linked immunosorbent assays (ELISA) were developed to test, in serum and mucosal samples, total IgG, total IgA, serum albumin, and anti-gp120 MN and anti-p24 LAI IgG and IgA levels. These ELISAs were optimized according to reagents and experimental conditions. Inter-
Further development of lactoferrin immunosensor (part III)
Campanella L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 186-193 (2010)
Danielle E Baranova et al.
Pathogens & immunity, 5(1), 89-116 (2021-06-18)
In cholera epidemics, the spread of disease can easily outpace vaccine control measures. The advent of technologies enabling the expression of recombinant proteins, including antibodies, in the milk of transgenic animals raises the prospect of developing a self-administered and cost-effective
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门