I2512
碘乙酸钠
powder, ≥98%
别名:
碘乙酸 钠盐
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关于此项目
线性分子式:
ICH2COONa
化学文摘社编号:
分子量:
207.93
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
206-165-7
MDL number:
Beilstein/REAXYS Number:
4009322
Application
用于修饰蛋白质中半胱氨酸残基的试剂。
用于修饰蛋白质中半胱氨酸残基的试剂。用于蛋白质测序（包括 Sanger 测序牛胰岛素）以防止 -SH 侧链的氧化。
用于修饰蛋白质中半胱氨酸残基的试剂。用于诱导动物骨关节炎模型系统，其模拟人类疾病的症状和组织病理学。
Biochem/physiol Actions
用于诱导大鼠骨关节炎样病变和功能障碍，用于测试软骨保护剂和诊断成像技术。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
406.4 °F
flash_point_c
208 °C
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Roberto E Guzman et al.
Toxicologic pathology, 31(6), 619-624 (2003-10-31)
Osteoarthritis (OA) is a degenerative joint disease characterized by joint pain and a progressive loss of articular cartilage. Studies to elucidate the pathophysiology of OA have been hampered by the lack of a rapid, reproducible animal model that mimics both
C Guingamp et al.
Arthritis and rheumatism, 40(9), 1670-1679 (1997-10-27)
To characterize the dose-responsiveness of morphologic and biochemical chondral changes relative to mobility in mono-iodoacetate (MIA)-induced osteoarthritis (OA) in rats. Rat mobility was assessed by biotelemetry. Articular lesions were characterized by macroscopic and histologic examinations. Cartilage proteoglycan metabolism was evaluated
Kuo-Ti Peng et al.
Clinical science (London, England : 1979), 133(21), 2171-2187 (2019-11-07)
Several diseases have been linked to particulate matter (PM) exposure. Outdoor activities, such as road running or jogging, are popular aerobic exercises due to few participatory limitations. Osteoarthritis (OA) is a progressive degenerative joint disease, usually observed at age 40
S E Bove et al.
Osteoarthritis and cartilage, 11(11), 821-830 (2003-11-12)
To describe an in vivo model in the rat in which change in weight distribution is used as a measure of disease progression and efficacy of acetaminophen and two nonsteroidal anti-inflammatory drugs (NSAIDs) in a model of monosodium iodoacetate (MIA)-induced
Matilde Tschon et al.
Cells, 9(7) (2020-07-02)
The purpose of this study was to verify the efficacy of a single intra-articular (i.a.) injection of a hyaluronic acid-chitlac (HY-CTL) enriched with two low dosages of triamcinolone acetonide (TA, 2.0 mg/mL and 4.5 mg/mL), in comparison with HY-CTL alone
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