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Merck
CN

I2282

Anti-Insulin-Like Growth Factor-II antibody produced in goat

affinity isolated antibody, lyophilized powder

别名:

Anti-IGF-II

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关于此项目

UNSPSC Code:
51111800
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), Neutral, WB
Citations:
1
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biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse

technique(s)

indirect ELISA: 0.5-1.0 μg/mL, neutralization: suitable, western blot: 0.1-0.2 μg/mL

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

mouse ... Igf2(16002)

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General description

Insulin-like growth factor II (IGF II) also refers as multiplication stimulating activity or MSA is a protein that is structurally similar to proinsulin. It is a potent mitogen for many cultured cells like mouse 3T3 cells, normal rat kidney cells, human or chicken fibroblasts and MCF-7 human breast carcinoma cells. IGF II possess mitogenic growth factor property and hence facilitates growth-promoting activity in embryonic development. Anti-Insulin-Like Growth Factor-II antibody can be used for neutralization assays. Goat anti-Insulin-Like Growth Factor-II antibody reacts specifically with recombinant mouse IGF-II. The product has also shown 25% (approx.) cross-reactivity with recombinant human IGF-II.

Immunogen

purified recombinant mouse insulin-like growth factor II, expressed in E. coli.

Application

Anti-Insulin-Like Growth Factor-II antibody can be used in ELISA and western blotting.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K P Karey et al.
Cancer research, 48(14), 4083-4092 (1988-07-15)
A completely serum-free assay method has been used to compare the mitogenic activities of polypeptide growth factors and estrogens with MCF-7 and T47D human breast cancer cells in culture. The lines were maintained in a viable, slowly dividing condition in

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