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一般描述
3-吲哚丙烯酸(IAA)是一种用于诱导基因转录的化学物质。该表达系统要求将目的基因克隆到含有 trpE 启动子的质粒中。
应用
3-吲哚丙烯酸已被用于在大肠杆菌中诱导核糖激酶的表达。
生化/生理作用
3-吲哚丙烯酸 (IAA) 由色氨酸代谢,这种转化通过肠道菌群进行。3-吲哚丙烯酸 (IAA) 是一种用于诱导基因转录的化学物质。IAA 诱导表达系统需要将目标基因克隆到含有色氨酸启动子的质粒中。它能促进肠上皮细胞的屏障功能。IAA 也有利于抗炎反应,并被视为炎症性肠病 (IBD) 的潜在治疗方法。它还参与多种细胞过程,包括凋亡、自噬、细胞增殖和迁移。另据报道,在肿瘤细胞中,IAA 可阻碍色氨酸代谢。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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