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安全信息

I1774

Sigma-Aldrich

伊枯草菌素A 来源于枯草芽孢杆菌

≥95% (HPLC), suitable for microbiological culture

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About This Item

CAS号:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.61

产品名称

伊枯草菌素A 来源于枯草芽孢杆菌, ≥95% (HPLC)

生物来源

Bacillus subtilis

质量水平

方案

≥95% (HPLC)

表单

powder

技术

microbiological culture: suitable

颜色

white to yellow

溶解性

ethanol: soluble 9.80-10.20 mg/mL

抗生素抗菌谱

fungi

作用机制

cell membrane | interferes

储存温度

2-8°C

应用

伊枯草菌素A 用于 Bacillomycin D(一种具有抗黄曲霉抗真菌活性的 伊枯草菌素)的研究

生化/生理作用

伊枯草菌素A 对致病性酵母和真菌有很强的抗真菌活性。它与靶细胞的细胞质膜相互作用,形成离子传导孔。其作用方式可归因于其与固醇和磷脂的相互作用。该化合物导致人红细胞释放外囊泡(exo-vesicle)。

其他说明

一个脂肽家族,其特征在于以C13-C17 β氨基脂肪酸环化的七肽。主要由C14-C15 β氨基酸组成。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Stephen Moran et al.
FEMS microbiology letters, 304(1), 69-73 (2010-01-15)
Bacillus sp. strain CS93, which was previously isolated from Pozol, was previously shown to produce iturin A, bacilysin and chlorotetaine. To investigate the biosynthetic mechanism of chlorotetaine production, the bac genes were amplified from genomic DNA of Bacillus sp. CS93
A L Moyne et al.
Journal of applied microbiology, 90(4), 622-629 (2001-04-20)
In a search for an antifungal peptide with a high activity against Aspergillus flavus, Bacillus subtilis AU195 was selected from a collection of isolates with antagonistic activity against A. flavus. To identify the antifungal peptides, a protein purification scheme was
Nopporn Thasana et al.
FEBS letters, 584(14), 3209-3214 (2010-06-15)
Subtulene A, a new cyclic lipopeptide, was isolated from the culture broth of Bacillus subtilis SSE4. This antibiotic compound contained the seven common alpha-amino acids, L-Asn-1, D-Tyr-2, D-Asn-3, L-Gln-4, L-Pro-5, D-Asn-6, L-Ser-7 and the unique beta-amino acid-8 present in the
Thimon, L., et al.
Cytobios, 79, 96-96 (1994)
Jun Yuan et al.
Journal of basic microbiology, 52(6), 721-730 (2012-05-15)
The primary mechanism underlying antagonism among microorganisms is the production of antagonistic substances called antibiotics that inhibit the growth of pathogens. In this study, the antagonistic substances produced by the Bacillus amyloliquefaciens strain NJN-6 that had antifungal activity against Fusarium

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