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Merck
CN

I134

Sigma-Aldrich

L-N5-(1-氨基乙基)鸟氨酸 盐酸盐

≥95% (HPLC)

别名:

L-NIO hydrochloride, L-Ornithine ψ-acetamidine hydrochloride

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About This Item

经验公式(希尔记法):
C7H15N3O2 · xHCl
分子量:
173.21 (free base basis)
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.26

质量水平

方案

≥95% (HPLC)

表单

powder

分子量

calculated mol wt 173.22 g/mol

储存条件

desiccated
under inert gas

颜色

white to beige

溶解性

H2O: 2 mg/mL, clear (warmed)

储存温度

−20°C

SMILES字符串

CC(NCCC[C@H](N)C(O)=O)=N.[H]Cl

InChI

1S/C7H15N3O2.ClH/c1-5(8)10-4-2-3-6(9)7(11)12;/h6H,2-4,9H2,1H3,(H2,8,10)(H,11,12);1H/t6-;/m0./s1

InChI key

JIBZSGQTCBWUKL-RGMNGODLSA-N

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应用

L-N5-(1-Iminoethyl) ornithine hydrochloride has been used to study the effects of the cytotoxic drug paclitaxel and carbachol (a cholinergic agonist) to induce death in breast tumor MCF-7 cells and the role of nitric oxide synthase (NOS) in this effect. It has also been used to study its effects on pulmonary arterial responses to sufentanil in the feline pulmonary vascular bed.

生化/生理作用

A potent irreversible inhibitor of nitric oxide synthase.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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International Review of Neurobiology, 42 (1998)
Participation of non-neuronal muscarinic receptors in the effect of carbachol with paclitaxel on human breast adenocarcinoma cells. Roles of nitric oxide synthase and arginase
Alejandro Javier Espa?ol
International Immunopharmacology, 29(1) (2015)
The effects of sufentanil in the feline pulmonary vascular bed
Alan D Kaye
European Journal of Pharmacology (2006)

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