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一般描述
IgA抗体是分泌性抗体，大量存在于胃肠道，呼吸道和泌尿生殖道的黏膜内壁，泪液，初乳和唾液中。因此，分泌性IgA有助于抵抗粘膜表面病原体的体液防御机制。
通过分级分离和离子交换分级分离从合并的正常人初乳中纯化人IgA。
通过分级分离和离子交换分级分离从合并的正常人初乳中纯化人IgA。
应用
纯化的IgA可用作ELISA、斑点免疫结合、免疫印迹、免疫扩散和免疫电泳等多种免疫测定的参照抗原、标准品、封闭剂或外壳蛋白。其他应用包括作为制备免疫原和固相免疫吸附剂的起始物料。来自人初乳的IgA用作ELISA（1 mg/ml）和凝胶电泳的标准品。
重悬
用缓冲盐水复溶（150mM 氯化钠）。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Susanna R Bidgood et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(37), 13463-13468 (2014-08-30)
IgA is the most prevalent antibody type on mucosal surfaces and the second most prevalent antibody in circulation, yet its role in immune defense is not fully understood. Here we show that IgA is carried inside cells during virus infection
P Kosuwon et al.
Beneficial microbes, 9(4), 541-552 (2018-04-11)
Little is known about the impact of nutrition on toddler gut microbiota. The plasticity of the toddler gut microbiota indicates that nutritional modulation beyond infancy could potentially impact its maturation. The objective of this study was to determine the effect
E Knop et al.
Investigative ophthalmology & visual science, 42(3), 566-574 (2001-02-27)
Mucosa-associated lymphoid tissue (MALT) specifically protects mucosal surfaces. In a previous study of the human conjunctiva, evidence was also found for the presence of MALT in the lacrimal sac. The present study, therefore, aims to investigate its morphology and topographical
Hannah Karen Mina Labayo et al.
EClinicalMedicine, 27, 100561-100561 (2020-10-13)
Norovirus (NV) causes acute gastroenteritis in infants. Humoral and fecal immunoglobulin A (IgA) responses have been correlated with protection against NV; however, the role of breast milk IgA against NV infection and associated diarrhea is still unknown. This study aimed
Lauri Vehkala et al.
Annals of medicine, 45(8), 501-510 (2013-10-18)
Obesity and type 2 diabetes (T2D) associate with increased oxidative stress. Malondialdehyde acetaldehyde (MAA) adducts have been suggested to be one of the antigenic epitopes in MDA-LDL responsible for the antibody recognition. Our aim was to investigate the associations between
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