Application
纯化的IgA可用作ELISA、斑点免疫结合、免疫印迹、免疫扩散和免疫电泳等多种免疫测定的参照抗原、标准品、封闭剂或外壳蛋白。其他应用包括作为制备免疫原和固相免疫吸附剂的起始物料。来自人初乳的IgA用作ELISA（1 mg/ml）和凝胶电泳的标准品。
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General description
IgA抗体是分泌性抗体，大量存在于胃肠道，呼吸道和泌尿生殖道的黏膜内壁，泪液，初乳和唾液中。因此，分泌性IgA有助于抵抗粘膜表面病原体的体液防御机制。
通过分级分离和离子交换分级分离从合并的正常人初乳中纯化人IgA。
通过分级分离和离子交换分级分离从合并的正常人初乳中纯化人IgA。
Preparation Note
用缓冲盐水复溶（150mM 氯化钠）。
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Lloyd S Robinson et al.
The Journal of biological chemistry, 294(14), 5230-5245 (2019-02-07)
Gardnerella vaginalis is abundant in bacterial vaginosis (BV), a condition associated with adverse reproductive health. Sialidase activity is a diagnostic feature of BV and is produced by a subset of G. vaginalis strains. Although its genetic basis has not been
A M Bakker-Zierikzee et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 17(2), 134-140 (2006-04-19)
Secretory immunoglobulin A (SIgA) plays an important role in the defence of the gastrointestinal tract. The level of faecal SIgA antibody is associated with increased neutralization and clearance of viruses. Formula-fed infants who lack the transfer of protective maternal SIgA
Susanna R Bidgood et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(37), 13463-13468 (2014-08-30)
IgA is the most prevalent antibody type on mucosal surfaces and the second most prevalent antibody in circulation, yet its role in immune defense is not fully understood. Here we show that IgA is carried inside cells during virus infection
Erick Sánchez-Salguero et al.
Maternal health, neonatology and perinatology, 5, 9-9 (2019-06-18)
Colostrum is the primary source of maternal immunoglobulin A (IgA) for the newborn. IgA participates in protection and regulation mechanisms of the immune response at the neonate's mucosa. Several studies have evaluated infectious diseases and vaccine protocols effects during pregnancy
Lauri Vehkala et al.
Annals of medicine, 45(8), 501-510 (2013-10-18)
Obesity and type 2 diabetes (T2D) associate with increased oxidative stress. Malondialdehyde acetaldehyde (MAA) adducts have been suggested to be one of the antigenic epitopes in MDA-LDL responsible for the antibody recognition. Our aim was to investigate the associations between
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