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安全信息

I0909

Sigma-Aldrich

6-Iodonordihydrocapsaicin

≥98% (HPLC), solid

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About This Item

经验公式（希尔记法）:
C17H26INO3
CAS号:
859171-97-4
分子量:
419.30
MDL编号:
MFCD09878233
UNSPSC代码:
12352200
PubChem化学物质编号:
24895913
NACRES:
NA.77

质量水平

100

方案

≥98% (HPLC)

表单

solid

储存条件

protect from light

颜色

white

溶解性

DMSO: ~44 mg/mL
H2O: insoluble

储存温度

2-8°C

SMILES字符串

CCCCCCCCC(=O)NCc1cc(OC)c(O)cc1I

InChI

1S/C17H26INO3/c1-3-4-5-6-7-8-9-17(21)19-12-13-10-16(22-2)15(20)11-14(13)18/h10-11,20H,3-9,12H2,1-2H3,(H,19,21)

InChI key

AAORACFZMYMFCG-UHFFFAOYSA-N

基因信息

human ... TRPV1(7442)

生化/生理作用

TRPV1 (V1) vanilloid receptor antagonist.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
074K4604

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Giovanni Appendino et al.
British journal of pharmacology, 139(8), 1417-1424 (2003-08-19)
1. The C-5 halogenation of the vanillyl moiety of resiniferatoxin, an ultrapotent agonist of vanilloid TRPV1 receptors, results in a potent antagonist for these receptors. Here, we have synthesized a series of halogenated derivatives of 'synthetic capsaicin' (nonanoyl vanillamide=nordihydrocapsaicin) differing
Yuriko Oi-Kano et al.
The Journal of nutritional biochemistry, 40, 209-218 (2016-12-13)
Oleuropein is the pungent principle of raw olives. Oleuropein aglycone (OA) is a major phenolic compound in extra virgin olive oil and the absorbed form of oleuropein. We aimed to determine the mechanism underlying the nutritional effects of oleuropein and
Daniela L Uliana et al.
Journal of psychopharmacology (Oxford, England), 34(9), 1043-1055 (2020-07-09)
Blockade of cannabinoid CB1 or vanilloid TRPV1 receptors in the ventromedial prefrontal cortex of rats respectively increases or decreases the conditioned emotional response during re-exposure to a context previously paired with footshocks. Although these mechanisms are unknown, they may involve
Manoela V Fogaça et al.
Pharmacology, biochemistry, and behavior, 129, 7-13 (2014-12-03)
Hemopressin (PVNFKFLSH; HP) is an orally active peptide derived from rat hemoglobin α-chain that could act as an inverse agonist at cannabinoid type 1 receptors (CB1). Here, we aim to investigate possible behavioral effects of HP in male Wistar rats
Azucena Perez-Burgos et al.
The Journal of physiology, 593(17), 3943-3957 (2015-06-19)
Certain probiotic bacteria have been shown to reduce distension-dependent gut pain, but the mechanisms involved remain obscure. Live luminal Lactobacillus reuteri (DSM 17938) and its conditioned medium dose dependently reduced jejunal spinal nerve firing evoked by distension or capsaicin, and

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