推荐产品
生物来源
rat
质量水平
重组
expressed in E. coli
方案
>97% (SDS-PAGE)
表单
lyophilized powder
效能
10-60 ng/mL ED50
分子量
predicted mol wt ~18.4 kDa
包装
pkg of 25 μg
杂质
endotoxin, tested
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
rat ... Il18(29197)
相关类别
生化/生理作用
Interleukin 18, also known as interferon-γ-inducing factor (IGIF) and IL-1γ, is a proinflammatory cytokine. It is an inducer of IFN-γ and Th1 (T cell helper type 1) responses (cell differentiation, cell-mediated cytotoxicity and inflammation). IL-18 induces the migration of microvascular endothelial cells.
外形
Lyophilized from 20 mM Tris , 500 mM NaCl, 0.5 mM EDTA, 1 mM TCEP, 0.05% (w/v) PEG8000 pH 8.0 with 5% Trehalose,and 50 μg BSA per μg IL-18
分析说明
The biological activity is measured by its ability to induce mouse IFN-γ production by activated mouse T cells.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Weiyi He et al.
Cytokine, 68(1), 32-39 (2014-05-03)
CD4(+) T cell polarization plays a critical role in the pathogenesis of allergy. How to modulate the skewed CD4(+) T cell polarization is less clear. The specific immunotherapy (SIT) is the only specific remedy for the treatment of allergic diseases;
Jochem W van der Veen et al.
Regulatory toxicology and pharmacology : RTP, 69(3), 371-379 (2014-05-13)
The currently available animal-free methods for the detection of skin sensitizing potential of chemicals seem promising. However, no single method is able to comprehensively represent the complexity of the processes involved in skin sensitization. To ensure a mechanistic basis and
Camille Guillerey et al.
Oncoimmunology, 4(9), e1027468-e1027468 (2015-09-26)
The Toll-like receptor 3 (TLR3) agonist poly(I:C) is a promising adjuvant for cancer vaccines due to its induction of potent antitumor responses occurring primarily through the activation of dendritic cells (DCs) and natural killer (NK) cells. However, little is known
M Dagenais et al.
Mucosal immunology, 9(1), 146-158 (2015-06-04)
Cellular inhibitors of apoptosis proteins (cIAPs) are critical arbiters of cell death and key mediators of inflammation and innate immunity. cIAP2 is frequently overexpressed in colorectal cancer and in regenerating crypts of ulcerative colitis patients. However, its corresponding functions in
Wei Guo et al.
Molecular pain, 10, 35-35 (2014-06-11)
It has been recently recognized that the descending serotonin (5-HT) system from the rostral ventromedial medulla (RVM) in the brainstem and the 5-HT3 receptor subtype in the spinal dorsal horn are involved in enhanced descending pain facilitation after tissue and
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