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Merck
CN

HT501128

Sigma-Aldrich

甲醛溶液,中性缓冲,10%

histological tissue fixative

别名:

甲醛

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About This Item

MDL编号:
UNSPSC代码:
12352114
PubChem化学物质编号:
NACRES:
NA.47

生物来源

synthetic

质量水平

浓度

10% formalin (approx. 4% formaldehyde)

颜色

colorless

pH值(酸碱度)

6.90-7.10

密度

1.080 g/cm3

应用

hematology
histology

储存温度

room temp

SMILES字符串

[O-]#[C+H2]

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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一般描述

10%中性缓冲的甲醛(NBF)是全世界范围内用于光学显微镜最常使用的固定剂,并且也是一种较为宽容的固定剂。10% NBF很适合于高通量的实验室,并只需要一段相对短的固定时间,但也可用于组织的长期储存。甲醛固定被视为在醛和蛋白之间形成的,并生成凝胶,从而在它们的体内关系上保留细胞性组成。一旦被正确固定后,组织应该可以承受后续的组织处理或染色阶段。

应用

10%甲醛中性缓冲溶液已用于3T3-L1前脂肪细胞系及小鼠胚胎成纤维细胞分化至脂肪细胞的油红-o染色。它已用于兔眼及糖尿病大鼠肠的组织学分析。
10%甲醛中性缓冲溶液已被用作一种常用的通用组织固定剂用于对组织进行固定。
常用的通用组织学固定剂。

外形

中性缓冲的溶液

象形图

Health hazardExclamation mark

警示用语:

Danger

危险分类

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Sens. 1

WGK

WGK 3

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Jonathan C J Wei et al.
Scientific reports, 7(1), 15885-15885 (2017-11-23)
Emerging micro-scale medical devices are showing promise, whether in delivering drugs or extracting diagnostic biomarkers from skin. In progressing these devices through animal models towards clinical products, understanding the mechanical properties and skin tissue structure with which they interact will
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Nu?o K, et al.
Journal of functional foods, 5(1) (2013)
Paul J Marchand et al.
Biomedical optics express, 8(7), 3343-3359 (2017-07-19)
We present a novel extended-focus optical coherence microscope (OCM) attaining 0.7 μm axial and 0.4 μm lateral resolution maintained over a depth of 40 μm, while preserving the advantages of Fourier domain OCM. Our system uses an ultra-broad spectrum from
Ablation of the transcriptional regulator Id1 enhances energy expenditure, increases insulin sensitivity, and protects against age and diet induced insulin resistance, and hepatosteatosis
Satyanarayana A, et al.
Faseb Journal, 26(1), 309-323 (2012)
Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo.
Hassler M R, et al.
Nucleic Acids Research, 46(5), 2185-2196 (2018)

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