HPA051870
抗-TMEM119 兔抗
Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
别名:
抗-跨膜蛋白119
产品名称
抗-TMEM119 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
product line
Prestige Antibodies® Powered by Atlas Antibodies
form
buffered aqueous glycerol solution
species reactivity
human
enhanced validation
independent
orthogonal RNAseq
Learn more about Antibody Enhanced Validation
technique(s)
immunohistochemistry: 1:500-1:1000
immunogen sequence
GDGARMVEGRGAEEEEKGSQEGDQEVQGHGVPVETPEAQEEPCSGVLEGAVVAGEGQGELEGSLLLAQEAQGPVGPPESPCACSSVHPS
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TMEM119(338773)
Application
兔抗-TMEM119抗体可用于免疫组化。
Biochem/physiol Actions
跨膜蛋白119（TMEM119）可作为成骨诱导因子并促进骨肉瘤细胞的增殖、迁移和的侵袭。(28} 它是在甲状旁腺激素（PTH）下游与成骨细胞的similar to mothers against decapentaplegic-3（Smad3）信号通路的关键分子。TMEM119被认为是一种以区别常驻小胶质细胞与人脑中血液来源的巨噬细胞的潜在小胶质细胞标志物。该基因的突变与骨肉瘤的发展有关。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
Prestige抗体®是经过高度表征和广泛验证的抗体，同时还有一个优点是其每个靶标的所有可用表征数据都可以通过位于此页面顶部产品名称下方的人类蛋白质图谱门户进行访问。Prestige抗体对其他蛋白质的独特性和低交叉反应性®是通过严密的抗原区域选择、亲和纯化和严格的选择来实现的。针对每一个Prestige Antibody都存在有对应的Prestige抗原对照，并可在链接区域内找到。
每个Prestige Antibody都是按照以下方法进行测试的：
每个Prestige Antibody都是按照以下方法进行测试的：
- 44例正常人类组织以及20例最常见癌症类型组织的IHC组织阵列。
- 364个人类重组蛋白片段的蛋白阵列。
General description
跨膜蛋白 119（TMEM119）由定位于人染色体 12q23.3 的基因编码。该编码蛋白属于跨膜蛋白家族。TMEM119 有一个 O-糖基化 N-端区。
Immunogen
跨膜蛋白119重组蛋白表位信号标签（PrEST）
Other Notes
相应抗原APREST85802
Physical form
在含有 40％ 甘油和 0.02％ 叠氮化钠的磷酸盐缓冲盐水（pH 7.2）中的溶液。
Legal Information
Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
法规信息
常规特殊物品
常规特殊物品
此项目有
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