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Merck
CN

HPA028115

Sigma-Aldrich

Anti-ARHGEF10L antibody produced in rabbit

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab3

别名:

Anti-FLJ10521, Anti-KIAA1626, Anti-Rho guanine nucleotide exchange factor (GEF) 10-like

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250 MG
¥1,245.18
1 G
¥3,260.71
5 G
¥10,782.06
25 G
¥22,395.62

¥1,245.18


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250 MG
¥1,245.18
1 G
¥3,260.71
5 G
¥10,782.06
25 G
¥22,395.62

About This Item

UNSPSC代码:
12352203
人类蛋白质图谱编号:
NACRES:
NA.43

¥1,245.18


有货详情


生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

产品线

Prestige Antibodies® Powered by Atlas Antibodies

表单

buffered aqueous glycerol solution

种属反应性

human

技术

immunofluorescence: 0.25-2 μg/mL
immunohistochemistry: 1:20-1:50

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此商品
104179B5388115944
application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

form

solid

form

solid

form

powder

form

solid

composition

Dye, ≥60% spectrophotometric assay

composition

Dye, ≥60% spectrophotometric assay

composition

Dye content, ≥60%

composition

Dye, ≥50% spectrophotometric assay

εmax

≥1500 at 623-628 nm in 50% ethanol at 0.005 g/L

εmax

-

εmax

-

εmax

≥810 at 630-635 nm in water at 0.005 g/L

Quality Level

400

Quality Level

200

Quality Level

200

Quality Level

400

一般描述

The gene encoding Rho guanine nucleotide exchange factor 10-like (ARHGEF10L) is localized on human chromosome 1p36.13. It possesses two suggested transmembrane helices, a Dbl homology domain and a putative WD40-like domain. ARHGEF10L mRNA is expressed in the pancreas and skeletal muscles.

免疫原

Rho guanine nucleotide exchange factor (GEF) 10-like recombinant protein epitope signature tag (PrEST)

应用

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies® protocols and other useful information.

生化/生理作用

Rho guanine nucleotide exchange factor 10-like (ARHGEF10L) has a role in the guanosine-5′-biphosphate/guanosine-5′-triphosphate (GDP/GTP) exchange of the Ras homolog gene family, member A (RhoA) protein in vitro. It has also been observed to take part in the activation of RhoA.

特点和优势

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

联系

Corresponding Antigen APREST76524

外形

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.

法律信息

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

An 18 gene expression-based score classifier predicts the clinical outcome in stage 4 neuroblastoma.
Formicola D
Journal of Translational Medicine, 14(1), 142-142 (2016)
GrinchGEF--a novel Rho-specific guanine nucleotide exchange factor.
Winkler S
Biochemical and Biophysical Research Communications, 335(4), 1280-1286 (2005)

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