跳转至内容

尊敬的客户:

目前国际形势复杂多变,关税政策尚不明朗,这可能对我们的产品价格产生一定影响。在此情况下,我们希望就订单事宜与您进行友好沟通。

基于当前的不确定性,如果您选择在此期间下单,我们将保留根据实际情况调整价格的权利。同时,我们也理解市场变化可能给您带来的困扰,因此如果在订单实际发货前因关税政策变动导致价格出现较大波动,默克将与您进行协商讨论并视情况对订单进行调整或取消。

关于应对近期政策变化的重要更新,请点击此处查看详情。

Merck
CN
所有图片(7)

主要文件

安全信息

HPA014246

Sigma-Aldrich

Anti-GHRL antibody produced in rabbit

enhanced validation

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

别名:

Anti-Appetite-regulating hormone precursor, Anti-Growth hormone secretagogue, Anti-Growth hormone-releasing peptide, Anti-M46 protein, Anti-Motilin-related peptide

登录查看公司和协议定价

选择尺寸

500 G
¥2,266.86

¥2,266.86


请联系客服了解存货情况


选择尺寸

变更视图
500 G
¥2,266.86

About This Item

UNSPSC代码:
12352203
人类蛋白质图谱编号:
NACRES:
NA.41

¥2,266.86


请联系客服了解存货情况

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

产品线

Prestige Antibodies® Powered by Atlas Antibodies

表单

buffered aqueous glycerol solution

种属反应性

human

增强验证

recombinant expression
orthogonal RNAseq
Learn more about Antibody Enhanced Validation

比较类似商品

查看完整比较结果

显示差异

1 of 4

此商品
767211478170135
XLD 琼脂 suitable for microbiology, NutriSelect® Basic

95586

XLD 琼脂

Millipore

70135

DCLS 琼脂

suitability

selective and differential for Klebsiella spp., selective and differential for Salmonella spp., selective and differential for enterobacteriaceae, selective and differential for Proteus spp., selective and differential for Shigella spp.

suitability

selective and differential for Citrobacter spp., selective and differential for Escherichia coli, selective and differential for Salmonella spp., selective and differential for Shigella spp., selective and differential for coliforms, selective and differential for enterobacteriaceae

suitability

Salmonella spp.

suitability

selective and differential for Salmonella spp., selective and differential for Shigella spp., selective and differential for Vibrio spp., selective and differential for Yersinia spp.

technique(s)

microbiological culture: suitable

technique(s)

microbiological culture: suitable

technique(s)

-

technique(s)

microbiological culture: suitable

sterility

non-sterile

sterility

non-sterile

sterility

non-sterile

sterility

-

composition

agar, 15 g/L , lactose, 7.5 g/L , phenol red, 0.08 g/L , sodium deoxycholate, 2.5 g/L , sucrose, 7.5 g/L , yeast extract, 3 g/L , ammonium ferric citrate, 0.8 g/L , sodium chloride, 5 g/L , xylose, 3.5 g/L , L-lysine hydrochloride, 5 g/L , sodium thiosulfate, 6.8 g/L

composition

agar, 18 g/L , ammonium-iron(III) citrate, 0.8 g/L , lactose, 7.5 g/L , L-lysine, 5 g/L , phenol-red, 0.08 g/L , proteose peptone No. 3, 1.6 g/L , sodium chloride, 5 g/L , sodium thiosulfate, 6.8 g/L , sucrose, 7.5 g/L , xylose, 3.75 g/L , yeast extract, 3 g/L

composition

agar, 15.0 g/L , ferric ammonium citrate, 0.80 g/L , lactose, 7.5 g/L , L-lysine hydrochloride, 5.0 g/L , phenol red, 0.08 g/L , sodium chloride, 5.0 g/L , sodium deoxycholate, 1.0 g/L , sodium thiosulfate, 6.8 g/L , sucrose, 7.5 g/L , xylose, 3.75 g/L , yeast extract, 3.0 g/L

composition

agar, 12.0 g/L , lactose, 5.0 g/L , neutral red, 0.03 g/L , sodium citrate, 10.5 g/L , sodium desoxycholate, 2.5 g/L , sodium thiosulfate, 5.0 g/L , special peptone, 10.0 g/L , sucrose, 5.0 g/L

application(s)

environmental
food and beverages
veterinary, microbiology

application(s)

clinical testing
environmental
food and beverages, microbiology

application(s)

food and beverages
water monitoring, microbiology

application(s)

clinical testing
environmental
food and beverages, microbiology

一般描述

The gene GHRL (ghrelin) encodes a prepropeptide that cleaves to form two proteins ghrelin and obestatin. The gene is mapped to human chromosome 3p25-p26 containing four exons and three introns. Ghrelin is mainly produced in stomach and pancreas.

免疫原

Appetite-regulating hormone precursor recombinant protein epitope signature tag (PrEST)

应用

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies® protocols and other useful information.

生化/生理作用

The peptide ghrelin, one of the cleavage products of prepropeptide produced from the GHRL gene, functions in stimulating food intake and controlling energy balance. It serves as an endogenous ligand for the growth hormone secretagogue receptor 1α (GHSR 1α) and has potent stimulating effects on the secretion of growth hormone and food intake. It regulates body weight on long-term and appetite on short-term. Preadipocyte differentiation stimulated by ghrelin is found to increase BMI and negatively regulate the anorexigenic effect of leptin. Polymorhism in the GHRL gene is linked to variations in BMI, blood pressure, high-density lipoproteins, low-density lipoproteins, serum cholesterol, blood glucose, and metabolic syndrome. The other cleavage peptide of prepropeptide produced from the GHRL gene, obestatin, is found to negatively regulate food intake and gastrointestinal motility, but does not participate in the release of growth hormone.

特点和优势

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

联系

Corresponding Antigen APREST72081

外形

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

法律信息

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到合适的产品?  

试试我们的产品选型工具.

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

新产品

  • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

    没有发现合适的版本?

    如果您需要特殊版本,可通过批号或批次号查找具体证书。

    已有该产品?

    在文件库中查找您最近购买产品的文档。

    访问文档库

    Yongfeng Yang et al.
    Behavioral and brain functions : BBF, 8, 11-11 (2012-03-01)
    Ghrelin (GHRL) is a pivotal peptide regulator of food intake, energy balance, and body mass. Weight gain (WG) is a common side effect of the atypical antipsychotics (AAPs) used to treat schizophrenia (SZ). Ghrelin polymorphisms have been associated with pathogenic
    Philippe Zizzari et al.
    Endocrinology, 148(4), 1648-1653 (2007-01-06)
    Administration of ghrelin, an endogenous ligand for the GH secretagogue receptor 1a (GHSR 1a), induces potent stimulating effects on GH secretion and food intake. However, more than 7 yr after its discovery, the role of endogenous ghrelin remains elusive. Recently

    我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

    联系客户支持