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Merck
CN

H9538

Sigma-Aldrich

HNE-DMA

hexane solution, ≥85% (GC)

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别名:
(e)-4- 羟基壬烯醛-二甲氧基乙烷, 4-HNE-DMA
经验公式(希尔记法):
C11H22O3
分子量:
202.29
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥85% (GC)

形式

hexane solution

运输

dry ice

储存温度

−20°C

SMILES字符串

CCCCCC(O)\C=C\C(OC)OC

InChI

1S/C11H22O3/c1-4-5-6-7-10(12)8-9-11(13-2)14-3/h8-12H,4-7H2,1-3H3/b9-8+

InChI key

ATGIHMSJAARJTF-CMDGGOBGSA-N

生化/生理作用

HNE 的稳定形式;有毒的自由基第二信使。

制备说明

要从 HNE-DMA 制备HNE:在室温下,通过温和的氮气流蒸发己烷。在 4°C 下,添加 1 ml (5 mg )或 0.4 ml (2 mg) 的1 mM低温 Hcl,搅拌 45 分钟或者盖上试剂瓶振荡 30 分钟。水解后,最初混浊的溶液变得几乎透明。现在该溶液的pH值为 ∼3,含∼5 mg (5 mg)或∼2 mg (2 mg)醛(HNE),并且至少可稳定存放24小时(如果保持在4°C)。在1 mL己烷溶液中加入6.8 mg HNE-DMA,水解后得到5 mg HNE。建议现配现用HNE溶液。

警示用语:

Danger

危险分类

Aquatic Chronic 2 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Inhalation - STOT SE 3

靶器官

Central nervous system, Nervous system

WGK

WGK 3

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品

分析证书(COA)

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