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Merck
CN

H9039

Sigma-Aldrich

氯化高铁血红素

from bovine, ≥90%

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别名:
氯(原卟啉酸)铁(III), 氯化血红素, 氯原卟啉IX铁(III), 高铁原卟啉IX氯, 高铁血红素(氯)
经验公式(希尔记法):
C34H32ClFeN4O4
CAS号:
分子量:
651.94
Beilstein:
5229914
EC 号:
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.61

生物来源

bovine

质量水平

检测方案

≥90%

形式

powder

技术

toxicology assay: suitable

溶解性

1.4 M NH4OH: soluble 25 mg/mL

储存温度

2-8°C

SMILES字符串

Cc1c(CCC(O)=O)c2cc3c(CCC(O)=O)c(C)c4cc5nc(cc6c(C)c(C=C)c(cc1n2)n6[Fe](Cl)n34)c(C=C)c5C

InChI

1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;

InChI key

BTIJJDXEELBZFS-HXFTUNQESA-K

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一般描述

血红素是在哺乳动物的血液中游离存在或与血红蛋白结合的小分子。这是宿主体内铁的另一种来源,它含有一个叫做血红素的卟啉环,其中含有Fe2+离子。

应用

血红素被用于研究利什曼病疫苗用脂磷聚糖-聚丙烯酸缀合物的缀合、表征和毒性。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the solubility of Hemin, Product H9039?

    Hemin can be dissolved in basic solution.  A 25 mg/ml solution can be prepared in 1.4 M ammonium hydroxide with heating to 95°C for less than 5 minutes. Hemin is also expected to be soluble in a sodium hydroxide solution. Hemin has been reported to be soluble at 1 mM concentration in DMSO, per Tomlinson and Ferguson, Proceedings of the National Academy of Sciences, 97, 5156-5160 (2000).  A 0.25% hemin solution can also be prepared in 50% triethanolamine solution.

  4. How stable is Hemin, Product H9039, in solution?

    Sigma-Aldrich has not evaluated the solution stability of hemin solutions.  Also, we have not found any information on solution storage in the literature. We recommend that solutions be prepared fresh.

  5. What is the shelf life for Hemin, Product H9039?

    There is no shelf life date assigned to this product. The guarantee of quality is for one year from the time of shipment for bottles stored as recommended.

  6. What are some applications for Hemin, Product H9039?

    Hemin-agarose has reportedly been prepared for use in affinity chromatography of heme-binding proteins.  See Tsutsui, K., Affinity chromatography of heme-binding proteins: Synthesis of hemin-agarose. Meth. Enzymol. 123, 331, (1986). Sigma supplies a hemin agarose, product H6390. Hemin can also be used as a component in culture media for the cultivation of bacteria, such as Leishmania tarentolae.

  7. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  8. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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