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Merck
CN

H8664

Sigma-Aldrich

甜叶菊甙元

≥98% (HPLC), powder

别名:

甜菊醇

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About This Item

经验公式(希尔记法):
C20H30O3 · xH2O
CAS号:
分子量:
318.45 (anhydrous basis)
MDL编号:
UNSPSC代码:
12161501
PubChem化学物质编号:
NACRES:
NA.77

质量水平

方案

≥98% (HPLC)

表单

powder

颜色

white to tan

溶解性

DMSO: >10 mg/mL

储存温度

2-8°C

SMILES字符串

O.C[C@@]12CCC[C@](C)([C@H]1CC[C@]34CC(=C)[C@](O)(CC[C@@H]23)C4)C(O)=O

InChI

1S/C20H30O3.H2O/c1-13-11-19-9-5-14-17(2,7-4-8-18(14,3)16(21)22)15(19)6-10-20(13,23)12-19;/h14-15,23H,1,4-12H2,2-3H3,(H,21,22);1H2/t14-,15-,17+,18+,19+,20-;/m0./s1

InChI key

SGPAFVVDOPSBEU-CRRYNOPCSA-N

生化/生理作用

甜菊醇是 hOAT1 和 hOAT3 有机阴离子转运蛋白的抑制剂。人有机阴离子转运蛋白 hOAT1 属于有机阴离子转运蛋白超家族,在抗 HIV 药物、抗肿瘤药物、抗生素、抗高血压药、抗炎药等临床重要药物的体内配置中起着至关重要的作用。甜菊醇是研究肾脏药物清除的有用工具。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Ravil N Khaybullin et al.
Bioorganic & medicinal chemistry letters, 22(22), 6909-6913 (2012-10-11)
New derivatives of steviol 1, the aglycone of the glycosides of Stevia rebaudiana, including a novel class of semisynthetic diterpenoids, namely macrocyclic ent-kauranes were synthesized. These compounds possess antituberculosis activity inhibiting the in vitro growth of Mycobacterium Tuberculosis (H37R(V) strain)
Stijn Ceunen et al.
Plant science : an international journal of experimental plant biology, 198, 72-82 (2012-12-04)
The effect of photoperiodism on steviol glycoside (SVgly) accumulation was investigated in Stevia rebaudiana. Topped plants were cultivated to develop new branches under a 16h or 8h photoperiod. During different ontogenetic phases, leaves, stems, lateral shoots, roots and reproductive organs
Venkata Sai Prakash Chaturvedula et al.
Molecules (Basel, Switzerland), 16(10), 8402-8409 (2011-10-05)
Synthesis of two ent-kaurane diterpene glycosides, steviol 19-O-β-D-glucopyranosiduronic acid (steviol glucuronide, 5), and 13-hydroxy ent-kaur-16-en-19-oic acid-β-D-glucopyranosyl ester (7) has been achieved from a common starting material, steviol, using phase transfer catalyst. Also, synthesis of an additional 17-nor-ent-kaurane glycoside, namely 13-methyl-16-oxo-17-nor-ent-kauran-19-oic
[Steviol glycosides as sweetener in diabetes?].
K Tuttas et al.
Deutsche medizinische Wochenschrift (1946), 137(15), 806-806 (2012-04-12)
Valerio Pieri et al.
Journal of agricultural and food chemistry, 59(9), 4378-4384 (2011-03-23)
The use of (1)H NMR spectroscopy for the characterization of Stevia rebaudiana extracts is presented. The developed method allows qualitative and quantitative determination of the major steviol glycosides in purified extracts and fractions obtained from various stages of the purification

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