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H8664

Sigma-Aldrich

甜叶菊甙元

≥98% (HPLC), powder

别名:

甜菊醇

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About This Item

经验公式（希尔记法）:
C20H30O3 · xH2O
CAS号:
471-80-7
分子量:
318.45 (anhydrous basis)
MDL编号:
MFCD20441965
UNSPSC代码:
12161501
PubChem化学物质编号:
329815252
NACRES:
NA.77

质量水平

100

方案

≥98% (HPLC)

表单

powder

颜色

white to tan

溶解性

DMSO: >10 mg/mL

储存温度

2-8°C

SMILES字符串

O.C[C@@]12CCC[C@](C)([C@H]1CC[C@]34CC(=C)[C@](O)(CC[C@@H]23)C4)C(O)=O

InChI

1S/C20H30O3.H2O/c1-13-11-19-9-5-14-17(2,7-4-8-18(14,3)16(21)22)15(19)6-10-20(13,23)12-19;/h14-15,23H,1,4-12H2,2-3H3,(H,21,22);1H2/t14-,15-,17+,18+,19+,20-;/m0./s1

InChI key

SGPAFVVDOPSBEU-CRRYNOPCSA-N

生化/生理作用

甜菊醇是 hOAT1 和 hOAT3 有机阴离子转运蛋白的抑制剂。
甜菊醇是 hOAT1 和 hOAT3 有机阴离子转运蛋白的抑制剂。人有机阴离子转运蛋白 hOAT1 属于有机阴离子转运蛋白超家族，在抗 HIV 药物、抗肿瘤药物、抗生素、抗高血压药、抗炎药等临床重要药物的体内配置中起着至关重要的作用。甜菊醇是研究肾脏药物清除的有用工具。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000127357
0000039681
0000039680
0000031164
0000020322

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J Isabella Zhang et al.
The Analyst, 137(13), 3091-3098 (2012-05-19)
Leaf spray mass spectrometry is explored as a fast and simple way for direct analysis of sweet glycosides in fresh untreated Stevia leaves without sample pretreatment. In this technique, a fresh triangular piece of Stevia leaf serves as both sample
Hitesh Kumar et al.
Gene, 492(1), 276-284 (2011-11-01)
Stevia [Stevia rebuaidana (Bertoni); family: Asteraceae] is known to yield diterpenoid steviol glycosides (SGs), which are about 300 times sweeter than sugar. The present work analyzed the expression of various genes of the SGs biosynthesis pathway in different organs of
M S Melis et al.
Brazilian journal of biology = Revista brasleira de biologia, 69(2), 371-374 (2009-08-14)
Stevia rebaudiana, a South American plant normally used as a natural herbal sweetener, has been suggested as exerting beneficial effects on human health, including as an antihypertensive and antihyperglycemic. The present experiment was undertaken to evaluate the renal excretion of
[Steviol glycosides as sweetener in diabetes?].
K Tuttas et al.
Deutsche medizinische Wochenschrift (1946), 137(15), 806-806 (2012-04-12)
Midori Takasaki et al.
Bioorganic & medicinal chemistry, 17(2), 600-605 (2009-01-10)
In a search for potential cancer chemopreventive agents from natural resources, stevioside (1), a sweetener, and six related compounds, including two aglycones steviol (6) and isosteviol (7), were screened in an in vitro assay for inhibitory effects on Epstein-Barr virus
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