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Merck
CN

H7891

Sigma-Aldrich

氯化六胺钴

for use in transformations, X-ray crystallography and NMR

别名:

氯化六氨合钴, 氯化钴六胺络合物

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About This Item

线性分子式:
[Co(NH3)6]Cl3
CAS号:
分子量:
267.48
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.52

等级

for molecular biology

质量水平

形式

powder

储存温度

room temp

SMILES字符串

N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Co+3]

InChI

1S/3ClH.Co.6H3N/h3*1H;;6*1H3/q;;;+3;;;;;;/p-3

InChI key

JXBGZYGSWFSYFI-UHFFFAOYSA-K

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一般描述

六胺钴 (III) 被认为是完全溶剂化镁的类似物,能够激活一些需要镁的酶。在 DNA 缩合研究中是有用的。

应用

适用于
  • DNA 缩合研究
  • 诱导 DNA 从 B 型向 A 型或 Z 型转化
  • 核酸晶体生长诱导
  • 三级 tRNA 相互作用的稳定性
  • 连接缓冲液的制备

象形图

Health hazard

警示用语:

Danger

危险分类

Aquatic Chronic 4 - Carc. 2 - Resp. Sens. 1 - Skin Sens. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Filip Senigl et al.
Cell reports, 29(12), 3902-3915 (2019-12-19)
Somatic hypermutation (SHM) introduces point mutations into immunoglobulin (Ig) genes but also causes mutations in other parts of the genome. We have used lentiviral SHM reporter vectors to identify regions of the genome that are susceptible ("hot") and resistant ("cold")
G Soslau et al.
Nucleic acids research, 14(18), 7237-7252 (1986-09-25)
These studies employed the synthetic linear DNA, poly dGdC, in the B and cobalt hexammine chloride (Co)-induced Z form to determine the effect of conformation on protein-DNA interactions. The rate of the reaction of the restriction endonucleases, Hha I and
Tumpa Sarkar et al.
Nucleic acids research, 33(1), 143-151 (2005-01-11)
The condensation of nucleic acids into well-defined particles is an integral part of several approaches to artificial cellular delivery. Improvements in the efficiency of nucleic acid delivery in vivo are important for the development of DNA- and RNA-based therapeutics. Presently
K E Rao et al.
Journal of biomolecular structure & dynamics, 7(2), 335-345 (1989-10-01)
Interaction of the DNA binding nonintercalators Netropsin, Distamycin and the mPD derivative with Z-DNA has been studied. It has been found that environmental factors like the solvent and added cations significantly modulate the interaction of these ligands with Z-DNA. However
Tong Zhang et al.
PloS one, 7(8), e43872-e43872 (2012-09-07)
Crystal structures of Thermotoga maritima magnesium transporter CorA, reported in 2006, revealed its homo-pentameric constructions. However, the structure of the highly conserved extracellular interhelical loops remains unsolved, due to its high flexibility. We have explored the configurations of the loops

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