H7509

羟丙基甲基纤维素

Name: 羟丙基 甲基纤维素
Brand: SIGMA

viscosity 2,600-5,600 cP, 2 % in H₂O(20 °C)(lit.)

别名:

2-Hydroxypropyl methyl cellulose ether

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化学文摘社编号:

9004-65-3

UNSPSC Code:

12352201

NACRES:

NA.25

MDL number:

MFCD00131360

主要文件

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产品名称

羟丙基甲基纤维素, viscosity 2,600-5,600 cP, 2 % in H₂O(20 °C)(lit.)

SMILES string

O3[C@H]([C@@H]([C@H]([C@@H]([C@H]3COCC(O)C)OCC(O)C)OCC(O)C)OCC(O)C)O[C@@H]4[C@H](O[C@H]([C@@H]([C@H]4OCC(O)C)OCC(O)C)OCC(O)C)COCC(O)C.O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1COC)OC)OC)OC)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2OC)OC)OC)COC

InChI

1S/C36H70O19.C20H38O11/c1-19(37)9-45-17-27-29(47-11-21(3)39)31(48-12-22(4)40)34(51-15-25(7)43)36(54-27)55-30-28(18-46-10-20(2)38)53-35(52-16-26(8)44)33(50-14-24(6)42)32(30)49-13-23(5)41;1-21-9-11-13(23-3)15(24-4)18(27-7)20(30-11)31-14-12(10-22-2)29-19(28-

InChI key

PUSNGFYSTWMJSK-GSZQVNRLSA-N

biological source

plant

form

powder

mol wt

~86 kDa

color

white to off-white

viscosity

2,600-5,600 cP, 2 % in H₂O(20 °C)(lit.)

solubility

water: 10 mg/mL, clear to very slightly hazy, colorless

storage temp.

room temp

Quality Level

200

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Application

水和非水系统的增稠剂、具有抗脂性的透明薄膜、粘合剂、润滑剂、空间稳定剂和保水剂。

羟丙基甲基纤维素(HPMC)已用于：

作为制备印刷油墨的粘度改性剂
作为制备羟磷灰石(HAP)的增黏剂
制备羟丙基甲基纤维素凝胶及复合体凝胶

Biochem/physiol Actions

羟丙基甲基纤维素(HPMC)可作为悬浮助剂、表面活性剂、润滑剂、保护性胶体和乳化剂。此外，HPMC聚合物的溶液形式具有热凝胶性，常用作粘合剂、增稠剂、成膜剂和保水剂。羟丙甲纤维素还具有表面活性。

Features and Benefits

溶于水，加热后可逆凝胶化，非离子，不与离子组分络合，具有表面活性和抗酶活性。溶液为假塑性。

General description

羟丙基甲基纤维素(HPMC)是水溶性聚合物，是纤维素的衍生物。这种多聚糖溶于水中会形成胶体。羟丙甲纤维素是由天然物质经人工制备而成的亲水胶体。甲氧基含量28-30%，羟丙基含量7-12%。

Other Notes

为了全面了解我们针对客户研究提供的各种多糖产品，建议您访问我们的碳水化合物分类页面。

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

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High-resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method.

Alexandre Goyon et al.

Electrophoresis, 39(16), 2083-2090 (2018-05-19)

The determination of mAb critical quality attributes (CQA) is crucial for their successful application in health diseases. A generic CZE method was developed for the high-resolution separation of various mAb charge variants, which are often recognized as important CQA. A

Transcription Factor PROX1 Suppresses Notch Pathway Activation via the Nucleosome Remodeling and Deacetylase Complex in Colorectal Cancer Stem-like Cells.

Jenny Högström et al.

Cancer research, 78(20), 5820-5832 (2018-08-30)

The homeobox transcription factor PROX1 is induced by high Wnt/β-catenin activity in intestinal adenomas and colorectal cancer, where it promotes tumor progression. Here we report that in LGR5+ colorectal cancer cells, PROX1 suppresses the Notch pathway, which is essential for

Optimization of capillary zone electrophoresis for charge heterogeneity testing of biopharmaceuticals using enhanced method development principles.

Bernd Moritz et al.

Electrophoresis, 38(24), 3136-3146 (2017-09-10)

CZE is a well-established technique for charge heterogeneity testing of biopharmaceuticals. It is based on the differences between the ratios of net charge and hydrodynamic radius. In an extensive intercompany study, it was recently shown that CZE is very robust

Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy.

Mylène Tajan et al.

Nature communications, 12(1), 366-366 (2021-01-16)

Many tumour cells show dependence on exogenous serine and dietary serine and glycine starvation can inhibit the growth of these cancers and extend survival in mice. However, numerous mechanisms promote resistance to this therapeutic approach, including enhanced expression of the de

An ethA-ethR-deficient Mycobacterium bovis BCG mutant displays increased adherence to mammalian cells and greater persistence in vivo, which correlate with altered mycolic acid composition.

Michelle Lay Teng Ang et al.

Infection and immunity, 82(5), 1850-1859 (2014-02-26)

Tuberculosis remains a major worldwide epidemic because of its sole etiological agent, Mycobacterium tuberculosis. Ethionamide (ETH) is one of the major antitubercular drugs used to treat infections with multidrug-resistant M. tuberculosis strains. ETH is a prodrug that requires activation within

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羟丙基甲基纤维素

viscosity 2,600-5,600 cP, 2 % in H₂O(20 °C)(lit.)

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关于此项目

主要文件

属性

产品名称

SMILES string

InChI

InChI key

biological source

form

mol wt

color

viscosity

solubility

storage temp.

Quality Level

相关类别

说明

Application

Biochem/physiol Actions

Features and Benefits

General description

Other Notes

安全信息

存储类别

wgk

flash_point_f

flash_point_c

ppe

文件

分析证书(COA)

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羟丙基 甲基纤维素

viscosity 2,600-5,600 cP, 2 % in H2O(20 °C)(lit.)

选择尺寸

关于此项目

主要文件

属性

产品名称

SMILES string

InChI

InChI key

biological source

form

mol wt

color

viscosity

solubility

storage temp.

Quality Level

相关类别

说明

Application

Biochem/physiol Actions

Features and Benefits

General description

Other Notes

安全信息

存储类别

wgk

flash_point_f

flash_point_c

ppe

文件

分析证书(COA)

已有该产品？

同行评审论文

技术文章和实验方案

商品

相关内容

技术服务

羟丙基甲基纤维素

viscosity 2,600-5,600 cP, 2 % in H₂O(20 °C)(lit.)