H6501
DL-β-羟基丁酸 钠盐
~98%, powder
别名:
(±)-3-羟基丁酸钠盐
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线性分子式:
C4H7O3Na
化学文摘社编号:
分子量:
126.09
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
205-774-5
MDL number:
产品名称
DL-β-羟基丁酸 钠盐, ~98%
InChI
1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1
InChI key
NBPUSGBJDWCHKC-UHFFFAOYSA-M
SMILES string
[Na].CC(O)CC(O)=O
assay
~98%
form
powder
solubility
water: 1 g/10 mL, clear, colorless
storage temp.
2-8°C
Quality Level
Application
DL-β-羟丁酸钠盐已用于：
- 作为标准物定量测定丹麦泽西奶牛血浆和乳汁 β-羟基丁酸
- 研究其在癫痫诱导大鼠中的抗惊厥作用
- 诱导荷斯坦奶牛高酮血症
Biochem/physiol Actions
β-羟基丁酸是存在于肝细胞瘤胃上皮中的酮体。其与乙酰乙酸酯的相互转化可影响酸碱平衡，并与荧光测定的（烟酰胺腺嘌呤二核苷酸）NAD +偶联产生NADH。高血浆水平的 β-羟基丁酸与糖尿病酮症酸中毒有关。它以单羧酸的形式穿过血脑屏障。β-羟基丁酸可能在帕金森病模型中对多巴胺能神经变性发挥保护作用。β-羟基丁酸是 G 蛋白偶联受体 (GPR109A) 的配体，有利于抑制奶牛垂体前叶细胞 (DCAPCs) 中生长激素 (GH) 和催乳素 (PRL) 基因的分泌、转录和翻译。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
此项目有
Influence of DL-beta-hydroxybutyric acid on cell proliferation and calcium influx
Cheng S, et al.
Biomacromolecules, 6(2), 593-597 (2005)
Fluorometric determination of beta-hydroxybutyrate in milk and blood plasma
Larsen T and Nielsen NI
Journal of Dairy Science, 88(6), 2004-2009 (2005)
Gwinyai E Chibisa et al.
Journal of animal science, 98(6) (2020-05-25)
Cattle need physically effective fiber to promote rumination and maintain rumen health, but economics favor the use of low-roughage feedlot diets. The study investigated the optimum barley silage proportion in barley-based finishing diets. Apparent total-tract digestibility (4-d total fecal collection)
Jianping Si et al.
Experimental and therapeutic medicine, 14(1), 765-770 (2017-07-05)
The present study aimed to investigate the anticonvulsant effects of β-hydroxybutyrate (BHB) in a kainic acid (KA)-induced rat seizure model. The concentrations of BHB and glucose were detected in the blood prior to exogenous BHB administration. Three different doses of
Emily R Cope et al.
Physiological genomics, 50(6), 468-477 (2018-04-07)
To identify molecular pathways that couple metabolic imbalances and reproduction, we randomly assigned 10 castrated male sheep to be centrally injected into the lateral ventricle through intracerebroventricular cannulas with 1 ml of β-hydroxybutyric acid sodium salt solution (BHB; 12,800 µmol/l)
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