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Merck
CN

H6382

Sigma-Aldrich

羟乙基淀粉

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About This Item

CAS号:
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25

生物来源

maize

表单

powder

SMILES字符串

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O.OCCOC[C@H]2O[C@H](OCCO)[C@H](OCCO)[C@@H](OCCO)[C@@H]2OCCO

InChI

1S/C16H32O11.C6H12O6/c17-1-6-22-11-12-13(23-7-2-18)14(24-8-3-19)15(25-9-4-20)16(27-12)26-10-5-21;7-1-2-3(8)4(9)5(10)6(11)12-2/h12-21H,1-11H2;2-11H,1H2/t12-,13-,14+,15-,16+;2-,3-,4+,5-,6+/m11/s1

InChI key

DNZMDASEFMLYBU-RNBXVSKKSA-N

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一般描述

羟乙基淀粉是一种非离子型淀粉衍生物。根据其体外分子量进行分类。6%浓度溶液通常以130kD分子量、0.38-0.45摩尔取代度为最优选择。 取代度:平均每10个葡萄糖单位中有1个-OH基转化为-OCH2CH2OH。

应用

羟乙基淀粉已用于研究其剪切响应性。还已用作精子分离、培养和冻存培养基中的高分子组分。

生化/生理作用

羟乙基淀粉(HES)是一种胶体,用于输液相关治疗。可作为血浆代用品。对重症败血症患者施用羟乙基淀粉会增加急性肾损伤风险。

联系

相似的羟乙基淀粉 (q.v.) 替换为 7-8 组/10 个葡萄糖单位。

制备说明

由玉米淀粉制备

储存分类代码

13 - Non Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the molecular weight of Hydroxyethyl starch, Product H6382?

    Product No. H6382 is not assayed for molecular weight. But based on the starch starting material, it is assumed to be greater than 1 million.

  4. Is Hydroxyethyl starch, Product H6382, soluble in water?

    Solubility in water has been reported as less than 20 mg/mL.  A 100 mg/mL preparation in water forms an opalescent suspension.

  5. Is Hydroxyethyl starch, Product H6382, the same as Hetastarch?

    No.  Hetastarch is more highly ethoxylated and partially hydrolyzed, making it much more soluble in water.  6% solutions of hetastarch in water or buffer are used as plasma volume extenders.

  6. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Hydroxyethyl starch 130/0.42 versus Ringer's acetate in severe sepsis
Perner A, et al.
The New England Journal of Medicine, 367(2), 124-134 (2012)
Shear-thickening fluids in biologically relevant agents
Kilbride P, et al.
Biorheology, 25(Preprint), 1-12 (2019)
Hydroxyethyl starch or saline for fluid resuscitation in intensive care
Myburgh JA
The New England Journal of Medicine, 367(20), 1901-1911 (2012)
An international view of hydroxyethyl starches
Treib J, et al.
Intensive Care Medicine, 25(3), 258-268 (1999)
A preliminary search for alternatives to albumin as a medium supplement for the culture of human sperm
Matson P and Tardif S
Reproductive Biology, 12(3), 329-331 (2012)

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