H5653
8-羟基-2′-脱氧鸟苷
≥98% (TLC), DNA damage biomaker
别名:
8-氧代-7,8-二氢-2′-脱氧鸟苷, 8-氧代-dG
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关于此项目
经验公式（希尔记法）:
C10H13N5O5
化学文摘社编号:
分子量:
283.24
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (TLC)
Quality level:
Application
8-羟基-2′-脱氧鸟苷已用于以下情形：
- 作为标准品，通过电化学检测分析正常和异常妊娠胎盘中的氧化DNA损伤
- 借助电化学检测(ECD)，作为标准品用于高效液相色谱法(HPLC)
- 作为HPLC标准品和氧化应激尿液标志物，评估绿咖啡豆提取物的潜在抗氧化活性(GCBE) 体内
- 作为标准品用于LC/MS/MS分析
Biochem/physiol Actions
8-羟基-2′-脱氧鸟苷的水平有助于评估喉癌个体的氧化应激和DNA损伤。因此它可以用作活性氧(ROS)诱导DNA损伤的主要生物标志物。
标记化合物通常指示与诱变和致癌作用相关的DNA损伤
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Medical Science Monitor Basic Research, 24(1), 47-47 (2018)
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