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Merck
CN

H5254

Sigma-Aldrich

橙皮苷

≥80% (HPLC)

别名:

3′,5,7-三羟基4′-甲氧基黄酮7-芸香, 橙皮素 7-鼠李糖苷, 橙皮素-7-芸香糖苷

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About This Item

经验公式(希尔记法):
C28H34O15
CAS号:
分子量:
610.56
Beilstein:
75140
EC 号:
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25

生物来源

Citrus sinensis (L.) Osbeck

质量水平

检测方案

≥80% (HPLC)

形式

powder

颜色

yellow to faint beige

mp

250-255 °C (dec.) (lit.)

溶解性

soluble, yellow to brown

储存温度

2-8°C

SMILES字符串

COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2

InChI

1S/C28H34O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-7,10,17,19,21-30,32-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1

InChI key

QUQPHWDTPGMPEX-QJBIFVCTSA-N

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应用

对橙皮苷和橙皮素(甙元)与 DMPC 脂质体的行为研究发现,甙元穿透更深,与“膜”结合更强。这可能解释了一般生物类黄酮苷元生物利用度较好的原因。

生化/生理作用

从柑橘中提取的黄酮类植物化学物质。为橙皮素的鼠李糖苷(芸香苷)。

其他说明

为了全面了解我们针对客户研究提供的各种二糖产品,建议您访问我们的碳水化合物分类页面。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Yomna S Mo'men et al.
Journal of biochemical and molecular toxicology, e22305-e22305 (2019-02-20)
Hesperidin is a flavanone glycoside that is found in the Citrus species and showed antioxidant, hepatoprotective as well as anticancer activity. This study investigated the effect of hesperidin on the PI3K/Akt pathway as a possible mechanism for its protective effect
Julia M Assini et al.
Current opinion in lipidology, 24(1), 34-40 (2012-12-21)
Citrus flavonoids are polyphenolic compounds with powerful biological properties. This review aims to summarize recent advances towards understanding the ability of citrus flavonoids to regulate lipid metabolism and other metabolic parameters relevant to the metabolic syndrome, type 2 diabetes and
Yong Yang et al.
European journal of medicinal chemistry, 58, 390-395 (2012-11-17)
We have identified a previously unknown function of the natural compound, hesperetin. Here, we demonstrate that this small molecular agent is able to inhibit the transforming growth factor-β (TGF-β) signaling pathway. Single-molecule force measurements and single-molecule fluorescence imaging show that
Leandro C Souza et al.
Progress in neuro-psychopharmacology & biological psychiatry, 40, 103-109 (2012-09-22)
The present study investigated a possible antidepressant-like activity of hesperidin using two predictive tests for antidepressant effect in mice: the forced swimming test (FST) and the tail suspension test (TST). Results demonstrated that hesperidin (0.1, 0.3 and 1 mg/kg, intraperitoneal
Binit Kumar et al.
Vascular pharmacology, 57(5-6), 201-207 (2012-09-13)
The purpose of the study was to evaluate vasculoprotective effects of Hesperetin (Hsp) in Streptozotocin induced diabetic rats. The study was carried out for a period of 24weeks and evaluated for angiogenic parameters (VEGF and PKC-β), retinal vascular leakage by

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