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Merck
CN

H4535

Sigma-Aldrich

Anti-Heme Oxygenase-1 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

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别名:
Anti-HO-1, Anti-HSP32
MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

antigen ~32 kDa

种属反应性

rat, mouse

技术

immunohistochemistry: 5 μg/mL
immunoprecipitation (IP): 10-20 μg/mL
western blot: 0.5-2 μg/mL

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... HMOX1(3162)
mouse ... Hmox1(15368)
rat ... Hmox1(24451)

免疫原

Synthetic peptide surrounding amino acids near the N-terminus of human HO-1.

应用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Western Blotting (1 paper)

外形

Solution in phosphate buffered saline containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

含少量动物源组分生物产品
常规特殊物品

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Lorenzo L F Glorie et al.
American journal of physiology. Renal physiology, 303(5), F681-F688 (2012-06-22)
Dipeptidyl peptidase 4 (DPP4) is an exopeptidase which modulates the function of its substrates, among which are insulin-releasing incretins. DPP4 inhibitors are currently used to improve glucose tolerance in type 2 diabetes patients. Inhibition of DPP4 exhibits protective effects on
Megan A Mahlke et al.
Pathobiology of aging & age related diseases, 1 (2011-01-01)
The anti-tumor effects of calorie restriction (CR) and the possible underlying mechanisms were investigated using ethylnitrosourea (ENU)-induced glioma in rats. ENU was given transplacentally at gestational day 15, and male offspring were used in this experiment. The brain from 4-
Alexander Leathem et al.
Antioxidants (Basel, Switzerland), 11(2) (2022-02-26)
The cyclic nitroxide TEMPOL exerts anti-oxidative and anti-inflammatory effects, and thus may provide therapeutic benefit in Parkinson's disease (PD), in which mitochondrial dysfunction, oxidative damage and inflammation have been implicated as pathophysiological mechanisms underlying the selective loss of dopaminergic neurons.
Abdulla K Salahudeen et al.
Transplantation, 91(2), 176-182 (2010-11-16)
Kidneys from brain-dead donors are cold preserved until transplanted. However, prolonged cold storage can contribute to allograft failure. Studies suggest that donor preconditioning with dopaminergics may reduce cold-ischemic transplant injury, but whether heme oxygenase (HO)-1 induction is an underlying mechanism
Qunli Cui et al.
Molecular medicine reports, 13(2), 1381-1388 (2015-12-10)
Parkinson's disease (PD) is an age-related complex neurodegenerative disease that affects ≤ 80% of dopaminergic neurons in the substantia nigra pars compacta (SNpc). It has previously been suggested that mitochondrial dysfunction, oxidative stress and oxidative damage underlie the pathogenesis of

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